Results 41 to 50 of about 44,041 (269)
Edusaintek, 2023 The background of this research is to help Micro, Small and Medium Enterprises (MSMEs) which need promotional media in the form of websites. Therefore the author has an idea to implement SEO (Search Engine Optimization). SEO (Search Engine Optimization)
Isbandi Isbandi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Qualitative ranking of Persian and non-Persian search engines in information retrieval of Islamic subjects [PDF]
کتابداری و اطلاعرسانی, 2016 Purpose: The purpose of this study was to determine the quality of the content of web pages in the Islamic domain retrieved by Persian and non Persian search engines. Methodology:This was an applied research carried out through descriptive survey. A self-
Naeimeh Morvarid +2 more
doaj
OPTIMIZING KEYWORD SEARCH FOR SEARCH ENGINES USING BLOCKCHAIN TECHNOLOGY [PDF]
Proceedings on Engineering SciencesThe traditional SEO landscape, reliant on algorithmic changes and privacy concerns, demands new solutions. This research explores the integration of blockchain technology into SEO to boost website visibility without compromising user privacy.
Bharti Aggarwal +2 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Using Internet Search Engines to Obtain Medical Information: A Comparative Study
Journal of Medical Internet Research, 2012 BackgroundThe Internet has become one of the most important means to obtain health and medical information. It is often the first step in checking for basic information about a disease and its treatment.
Wang, Liupu +5 more
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