Results 51 to 60 of about 185,887 (355)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

A novel approach for the prediction of treadmill test in cardiology using data mining algorithms implemented as a mobile application

open access: yesIndian Heart Journal, 2018
Objective: To develop a mobile app called “TMT Predict” to predict the results of Treadmill Test (TMT), using data mining techniques applied to a clinical dataset using minimal clinical attributes. To prospectively test the results of the app in realtime
A. Jerline Amutha   +2 more
doaj   +1 more source

Search trees: Metric aspects and strong limit theorems

open access: yes, 2014
We consider random binary trees that appear as the output of certain standard algorithms for sorting and searching if the input is random. We introduce the subtree size metric on search trees and show that the resulting metric spaces converge with ...
Grübel, Rudolf
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Architecture modeling for system collaborative combat based on unified architecture framework (UAF) [PDF]

open access: yesZhihui kongzhi yu fangzhen
Facing the continuous improvement of war complexity under the trend of system-of-systems confrontation,this paper introduces MBSE to the modeling design of complex system-of-systems combat. Adopting Unified Architecture Framework, a modeling method based
LI Delin, ZHANG Yuchen, WANG Jun, LIU Naihao
doaj   +1 more source

Idempotent permutations [PDF]

open access: yes, 2013
Together with a characteristic function, idempotent permutations uniquely determine idempotent maps, as well as their linearly ordered arrangement simultaneously. Furthermore, in-place linear time transformations are possible between them.
Cetin, A. Emre
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

ONTOLOGY OF COMPUTATIONAL EXPERIMENT ORGANIZATION IN PROBLEMS OF SEARCHING AND SORTING

open access: yesÌнформаційні технології в освіті, 2011
Ontologies are a key technology of semantic processing of knowledge. We examine a methodology of ontology’s usage for the organization of computational experiment in problems of searching and sorting in studies of the course "Basics of algorithms and ...
A. Spivakovsky, N. Osipova
doaj  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Improved neighbor list algorithm in molecular simulations using cell decomposition and data sorting method

open access: yes, 2004
An improved neighbor list algorithm is proposed to reduce unnecessary interatomic distance calculations in molecular simulations. It combines the advantages of Verlet table and cell linked list algorithms by using cell decomposition approach to ...
Allen   +23 more
core   +1 more source

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