Results 61 to 70 of about 172,936 (332)
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
A New Hybrid Metaheuristic Algorithm for Multiobjective Optimization Problems
International Journal of Computational Intelligence Systems, 2020 The elitist nondominated sorting genetic algorithm (NSGA-II) is hybridized with the sine-cosine algorithm (SCA) in this paper to solve multiobjective optimization problems.
M.A. Farag +5 more
doaj +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
, 2010 We investigate ways in which an algorithm can improve its expected performance by fine-tuning itself automatically with respect to an unknown input distribution D. We assume here that D is of product type.
Ailon, Nir +5 more
core +2 more sources
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Improving the performance of bubble sort using a modified diminishing increment sorting [PDF]
, 2009 Sorting involves rearranging information into either ascending or descending order. There are many sorting algorithms, among which is Bubble Sort.
Oyelami, O. M.
core
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
CREATION SOFTWARE COMPLEX FOR LECTURE MATERIALS CREATION AND SUGGESTS
Ìнформаційні технології в освіті, 2010 The article analyzes weaknesses of existing tools for lecture materials creation and suggests ways to address them. New modular complex architecture is proposed, which will support different types of lecture materials, templates, interactive elements ...
V. V. Polinovskyi, V. A. Gerasymenko
doaj
Art to Commerce: The Trajectory of Popular Music Criticism [PDF]
IASPM Journal, 2014 This article reports the results of a content and textual analysis of popular music criticism from the 1960s to the 2000s to discern the extent to which criticism has shifted focus from matters of music to matters of business.
Thomas Conner, Steve Jones
doaj +1 more source
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source