Results 111 to 120 of about 3,764 (237)

Acceptability by community health workers in Senegal of combining community case management of malaria and seasonal malaria chemoprevention [PDF]

open access: yesMalaria Journal, 2013
Community case management of malaria (CCMm) and seasonal malaria chemoprevention (SMC) are anti-malarial interventions that can lead to substantial reduction in malaria burden acting in synergy. However, little is known about the social acceptability of these interventions.
Tine, Roger Ck   +11 more
openaire   +3 more sources

Effect of seasonal malaria chemoprevention plus azithromycin on Plasmodium falciparum transmission: gametocyte infectivity and mosquito fitness

open access: yesMalaria Journal, 2021
Background Seasonal malaria chemoprevention (SMC) consists of administration of sulfadoxine-pyrimethamine (SP) + amodiaquine (AQ) at monthly intervals to children during the malaria transmission period.
Koudraogo Bienvenue Yaméogo   +13 more
doaj   +1 more source

Comparison of home fortification with two iron formulations among Kenyan children: Rationale and design of a placebo-controlled non-inferiority trial. [PDF]

open access: yes, 2017
INTRODUCTION: Home fortification powders containing iron and other micronutrients have been recommended by World Health Organisation to prevent iron deficiency anaemia in areas of high prevalence.
Andango, Pauline EA   +7 more
core   +2 more sources

Lingering challenges in malaria elimination efforts in sub‐Saharan Africa: Insights and potential solutions

open access: yesHealth Science Reports, Volume 7, Issue 6, June 2024.
Abstract Introduction Between 2000 and 2015, significant gains were recorded in reducing the global burden of malaria due to enhanced global collaboration and increased funding. However, progress has stagnated post‐2015, and the COVID‐19 pandemic seems to have reversed some of these gains, necessitating a critical reevaluation of interventions.
Lukman Lawal   +12 more
wiley   +1 more source

Assessing the effect of seasonal malaria chemoprevention on malaria burden among children under 5 years in Burkina Faso

open access: yesMalaria Journal, 2022
Background In 2014, the Burkina Faso government launched the Seasonal Malaria Chemoprevention (SMC) programme. Expected benefit was a 75% reduction of all malaria episodes and a 75% drop of severe malaria episodes.
Fati Kirakoya-Samadoulougou   +4 more
doaj   +1 more source

Safety and benefits of interventions to increase folate status in malaria-endemic areas. [PDF]

open access: yes, 2017
For decades, folic acid has routinely been given to prevent or treat anaemia in children, pregnant women and people with sickle cell disease. However, there is no conclusive evidence that folate deficiency anaemia constitutes a public health problem in ...
Adjalla   +88 more
core   +1 more source

Medication adherence framework: A population‐based pharmacokinetic approach and its application in antimalarial treatment assessments

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 13, Issue 5, Page 795-811, May 2024.
Abstract We reported here on the development of a pharmacometric framework to assess patient adherence, by using two population‐based approaches – the percentile and the Bayesian method. Three different dosing strategies were investigated in patients prescribed a total of three doses; (1) non‐observed therapy, (2) directly observed administration of ...
Junjie Ding   +2 more
wiley   +1 more source

Large-scale delivery of seasonal malaria chemoprevention to children under 10 in Senegal: an economic analysis. [PDF]

open access: yes
Seasonal Malaria Chemoprevention (SMC) is recommended for children under 5 in the Sahel and sub-Sahel. The burden in older children may justify extending the age range, as has been done effectively in Senegal.
Cissé, Badara   +9 more
core   +1 more source

Estimation of trajectory of protective efficacy in infectious disease prevention trials using recurrent event times

open access: yesStatistics in Medicine, Volume 43, Issue 9, Page 1759-1773, 30 April 2024.
In studies of infectious disease prevention, the level of protective efficacy of medicinal products such as vaccines and prophylactic drugs tends to vary over time. Many products require administration of multiple doses at scheduled times, as opposed to one‐off or continual intervention. Accurate information on the trajectory of the level of protective
Yin Bun Cheung   +4 more
wiley   +1 more source

Co-morbidity of malnutrition with falciparum malaria parasitaemia among children under the aged 6–59 months in Somalia: a geostatistical analysis [PDF]

open access: yes, 2018
Background Malnutrition and malaria are both significant causes of morbidity and mortality in African children. However, the extent of their spatial comorbidity remains unexplored and an understanding of their spatial correlation structure would inform ...
Berkley, James   +7 more
core   +3 more sources

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