Immunity, Inflammation and Disease, Volume 12, Issue 9, September 2024.Abstract Background Severe Plasmodium falciparum malarial anemia is still the principal cause of death in children in underdeveloped countries. An imbalance between proinflammatory and anti‐inflammatory cytokines is associated with malaria progression.
Charles Nkansah +25 more
wiley +1 more source
Co-morbidity of malnutrition with falciparum malaria parasitaemia among children under the aged 6–59 months in Somalia: a geostatistical analysis [PDF]
, 2018 Background Malnutrition and malaria are both significant causes of morbidity and mortality in African children. However, the extent of their spatial comorbidity remains unexplored and an understanding of their spatial correlation structure would inform ...
Berkley, James +7 more
core +3 more sources
Introducing field digital data collection systems into seasonal malaria chemoprevention campaigns: opportunities for robust evidence development and national e-health strategies [PDF]
, 2022 Kanda Balla +20 more
openalex +1 more source
Epidemiology of malaria in an area of seasonal transmission in Niger and implications for the design of a seasonal malaria chemoprevention strategy [PDF]
Malaria Journal, 2013 Abstract Background Few data are available about malaria epidemiological situation in Niger. However, implementation of new strategies such as vaccination or seasonal treatment of a target population requires the knowledge of baseline epidemiological features of malaria.
Guillebaud, Julia +10 more
openaire +5 more sources
Malaria Journal, 2021 Background Seasonal malaria chemoprevention (SMC) consists of administration of sulfadoxine-pyrimethamine (SP) + amodiaquine (AQ) at monthly intervals to children during the malaria transmission period.
Koudraogo Bienvenue Yaméogo +13 more
doaj +1 more source
Health Science Reports, Volume 7, Issue 6, June 2024.Abstract Introduction Between 2000 and 2015, significant gains were recorded in reducing the global burden of malaria due to enhanced global collaboration and increased funding. However, progress has stagnated post‐2015, and the COVID‐19 pandemic seems to have reversed some of these gains, necessitating a critical reevaluation of interventions.
Lukman Lawal +12 more
wiley +1 more source
The Evolving Landscape of Malaria Prevention Strategies: A Review of Recent Developments
PathogensMalaria continues to impose a devastating disease burden globally despite control efforts spanning decades. Its elimination has been hindered by parasite and vector complexity and emerging drug and insecticide resistance, along with unremitting barriers ...
Yathavi Charavanamuttu +3 more
doaj +1 more source
A Public Health Paradox: The Women Most Vulnerable to Malaria Are the Least Protected [PDF]
, 2016 Raquel Gonzalez and colleagues highlight an urgent need to evaluate antimalarials that can be safely administered to HIV-infected pregnant women on antiretroviral treatment and cotrimoxazole ...
González, Raquel +4 more
core +3 more sources
CPT: Pharmacometrics &Systems Pharmacology, Volume 13, Issue 5, Page 795-811, May 2024.Abstract We reported here on the development of a pharmacometric framework to assess patient adherence, by using two population‐based approaches – the percentile and the Bayesian method. Three different dosing strategies were investigated in patients prescribed a total of three doses; (1) non‐observed therapy, (2) directly observed administration of ...
Junjie Ding +2 more
wiley +1 more source
Travel and the emergence of high-level drug resistance in Plasmodium falciparum in southwest Uganda: results from a population-based study. [PDF]
, 2017 BACKGROUND: The I164L mutation on the dhfr gene confers high level resistance to sulfadoxine-pyrimethamine (SP) but it is rare in Africa except in a cluster of reports where prevalence >10% in highland areas of southwest Uganda and eastern Rwanda.
Abeku, Tarekegn A +8 more
core +1 more source