Clinical and Translational Science, Volume 17, Issue 4, April 2024.Abstract Drug resistance to sulfadoxine‐pyrimethamine and amodiaquine threatens the efficacy of malaria chemoprevention interventions in children and pregnant women. Combining pyronaridine (PYR) and piperaquine (PQP), both components of approved antimalarial therapies, has the potential to protect vulnerable populations from severe malaria.
Andrea Kuemmerle +9 more
wiley +1 more source
A Public Health Paradox: The Women Most Vulnerable to Malaria Are the Least Protected [PDF]
, 2016 Raquel Gonzalez and colleagues highlight an urgent need to evaluate antimalarials that can be safely administered to HIV-infected pregnant women on antiretroviral treatment and cotrimoxazole ...
González, Raquel +4 more
core +3 more sources
Journal of Parasitology Research, Volume 2024, Issue 1, 2024.Background. Natural medicinal products are commonly used as a remedy against malaria infections in African populations and have become a major source of information for the screening of new and more effective antiplasmodial molecules. Therefore, in vitro studies are needed to validate the efficacy of these medicinal products and to explore the ...
Hamirath O. Lagnika +10 more
wiley +1 more source
Malaria Prevention Strategies in South Sudan
South Sudan Medical Journal, 2020 The whole of South Sudan is endemic for malaria, with high transmission in the country throughout the year. Malaria is the leading cause of illness and death in children under five years. In 2019, the malaria incidence (all ages) was estimated at 246 per
Harriet Akello Pasquale
doaj
Travel and the emergence of high-level drug resistance in Plasmodium falciparum in southwest Uganda: results from a population-based study. [PDF]
, 2017 BACKGROUND: The I164L mutation on the dhfr gene confers high level resistance to sulfadoxine-pyrimethamine (SP) but it is rare in Africa except in a cluster of reports where prevalence >10% in highland areas of southwest Uganda and eastern Rwanda.
Abeku, Tarekegn A +8 more
core +1 more source
A Bayesian spatio-temporal framework to assess the effect of seasonal malaria chemoprevention on children under 5 years in Cameroon from 2016 to 2021 using routine data [PDF]
, 2023 Arnold Fottsoh Fokam +4 more
openalex +1 more source
Review of mass drug administration for malaria and its operational challenges. [PDF]
, 2015 Mass drug administration (MDA) was a component of many malaria programs during the eradication era, but later was seldomly deployed due to concerns regarding efficacy and feasibility and fear of accelerating drug resistance.
Chen, Ingrid +12 more
core +1 more source
Progress Report on Implementation of Regional Committee Resolution AFR/RC59/R3 on Accelerated Malaria Control [PDF]
, 2013 Several resolutions have been adopted and commitments made to scale up malaria control towards elimination in the African Region. These include United Nations, African Union, regional economic communities, World Health Assembly and Regional Committee ...
Diarra, Tieman +3 more
core
Reactive community-based self-administered treatment against residual malaria transmission: study protocol for a randomized controlled trial [PDF]
, 2018 Background: Systematic treatment of all individuals living in the same compound of a clinical malaria case may clear asymptomatic infections and possibly reduce malaria transmission, where this is focal.
A Kaneko +42 more
core +3 more sources
PLoS ONE, 2023 Seasonal Malaria chemoprevention (SMC) is one of the large-scale life-saving malaria interventions initially recommended for the Sahel subregion, including Burkina Faso and recently extended to other parts of Africa.
Paul Sondo +13 more
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