Results 91 to 100 of about 14,450 (260)

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

A case of orbital sebaceous gland carcinoma developing in an anophthalmic socket 65 years after enucleation

Clinical Ophthalmology, 2013
Motoko Shibata,1,* Yoshihiko Usui,1,* Shunichiro Ueda,1 Hajime Matsumura,2 Toshitaka Nagao,3 Hiroshi Goto1 1Department of Ophthalmology, 2Department of Plastic and Reconstructive Surgery, 3Department of Anatomic Pathology, Tokyo Medical University, Tokyo,
Shibata M, Usui Y, Ueda S, Matsumura H, Nagao T, Goto H   +5 more
doaj  

S1‐Guideline Sebaceous Carcinoma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft
SummarySebaceous gland carcinomas are rare malignant cutaneous adnexal tumors with sebocytic differentiation. The typical predilection area is the head and neck region, where sebaceous gland carcinomas are the most common malignant adnexal tumors of the skin.
Utikal, Jochen, Nagel, Pia, Müller, Verena, Becker, Jürgen C., Dippel, Edgar, Frisman, Alexander, Gschnell, Martin, Griewank, Klaus, Hadaschik, Eva, Helbig, Doris, Hillen, Uwe, Leiter, Ulrike, Pföhler, Claudia, Krönig, Lisa, Ziemer, Mirjana, Ugurel, Selma   +15 more
openaire   +2 more sources

Harnessing microbial metabolism and nutrition to target the gut–mammary axis for better livestock production and health

iMetaOmics, EarlyView.
The gut–mammary axis integrates intestinal health with mammary function through neural, endocrine, and immune pathways. Nutritional interventions (probiotics, prebiotics, metabolites) improve gut microecology, generating microbial signals that travel via the axis to the mammary gland. There, they relieve inflammation, enhance milk quality and lactation,
Aolong Zhou, Cheng Guo, Mahmoud M. Abdelsattar, Ahmad R. Musa, Mequanint Biks, Abdullahi A. Musa, Shahnaz Rahman, Abera Teshome Aleli, Pei Zhong, Jiawei Zhang, Junwei Cui, Xiyan Kou, Qingyuan Yu, Caijuan Yue, Qin Li, Dan Zhang, Zixuan Peng, Ao Ren, Ziqi Tian, Ziqi Liu, Yaona Zhang, Lili Zhang, Dina Karmallah, Naifeng Zhang, Tao Ma, Yan Tu, Qiyu Diao, Guijie Zhang, Xiaofeng Xu, Yanliang Bi   +29 more
wiley   +1 more source

Climate change amplifies global mycotoxin exposure: Emerging risks and sustainable solutions

iMetaOmics, EarlyView.
Climate change intensifies mycotoxin contamination through rising temperatures, elevated CO2, and altered precipitation. Global surveys reveal a high and widespread prevalence of major mycotoxins in staple cereals, with low‐income countries bearing the greatest burden.
Mengyao Xue, Zheng Qu, Tingting Jiang, Antonio F. Logrieco, Antonio Moretti, Ke Dong, Yanpo Yao, Qi Zhang, Peiwu Li   +8 more
wiley   +1 more source

Western Diet Combined With Chemical Induction: A Strategy for Rapid Development of MASLD Pathology in Mice

iNew Medicine, EarlyView.
ABSTRACT Objective The molecular mechanisms underlying the development of metabolic‐dysfunction‐associated steatotic liver disease (MASLD) are essential for developing appropriate treatments. The purpose of this study was to establish an MASLD model in mice with rapid and consistent progression.
Ting‐Ting Chen, Nan Li, Shuo Wang, Miao Sun, Rui Yang, Shi‐Hao Zhang, Xiao‐Lei Li, Chen Dong, Ke‐Yuan Chen, Wu‐Yi Sun, Na Zhou   +10 more
wiley   +1 more source

Discriminating Chemoresistant and Chemosensitive Tubo‐Ovarian High‐Grade Serous Carcinoma Cells With Raman Microscopy

Journal of Raman Spectroscopy, EarlyView.
Confocal Raman microscopy combined with multivariate analysis distinguishes cisplatin‐resistant and ‐sensitive tubo‐ovarian high‐grade serous carcinoma cell lines. ABSTRACT Chemoresistance is a major obstacle to effective cancer treatment, particularly in tubo‐ovarian high‐grade serous carcinoma (HGSC), the most lethal gynaecological malignancy ...
Elina Harju, Parisa Movahedi, Teemu Tomberg, Sara J. Fraser‐Miller, Francesco Piga, Jukka Saarinen, Kathleen J. Sircombe, Jacopo Zini, Jukka Heikkonen, Anna Laury, Sarah Hook, Keith C. Gordon, Tapio Pahikkala, Clare J. Strachan   +13 more
wiley   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori, Pedro Garcia Caparros, Antonella Castagna, Luisa Custódio, Valentina Lazazzara, Claus Krogh Madsen, Felicia Menicucci, Maria João Rodrigues, Katalin Solymosi, Jose Ramon Acosta Motos   +9 more
wiley   +1 more source

Dermatologic Best Practices for Manicures and Nail Care: A Systematic Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Manicure and pedicure procedures are widely viewed as benign cosmetic practices, yet emerging evidence links them to various dermatologic complications, including dermatitis, infection, photodamage and, in rare cases, cutaneous malignancy.
Nivetha Aravind, Olivia Burke, Brian W. Morrison   +2 more
wiley   +1 more source