Antipsychotic use in a resource-limited setting: Findings in an Eastern Cape psychiatric hospital
Background: Second-generation antipsychotics (SGAs) are commonly prescribed despite the fact that large, naturalistic studies have failed to show superior efficacy and tolerability when compared with first-generation antipsychotics (FGAs). In addition to
Ingrid Eloff +2 more
doaj +1 more source
Comparison of relapse rates of depot and oral antipsychotics in patients with schizophrenia [PDF]
Introduction: Antipsychotics are the mainstay of treatment in schizophrenia. First-generation and second-generation antipsychotics are available as oral and depot formulations.
Ball, Patrick +4 more
core +1 more source
No association of a set of candidate genes on haloperidol side effects. [PDF]
We previously investigated a sample of patients during an active phase of psychosis in the search for genetic predictors of haloperidol induced side effects.
De Ronchi, Diana +8 more
core +10 more sources
Second-generation antipsychotics - a panacea?
NO ABSTRACT ...
Paul D Carey, Dan Stein, Robin Emsley
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Antioxidant Properties of Second-Generation Antipsychotics: Focus on Microglia
Recent studies suggest a primary role of oxidative stress in an early phase of the pathogenesis of schizophrenia and a strong neurobiological link has been found between dopaminergic system dysfunction, microglia overactivation, and oxidative stress ...
Giuseppe Caruso +5 more
doaj +1 more source
Effect of melatonin in reducing second-generation antipsychotic metabolic effects: A double blind controlled clinical trial [PDF]
Introduction The use of second-generation atypical antipsychotics has an increasing role in the development of metabolic syndrome. However, these medications due to metabolic disorders can lead to an increased risk of cardiovascular disease and ...
Agahi, M. +4 more
core +1 more source
Schizophrenia: Practical prescribing of antipsychotics [PDF]
Schizophrenia is commonly treated with antipsychotics. This article presents a major overview of prescribing antipsychotic for the non-medical prescriber.
Haygarth, Lynn, Hemingway, Steve
core +1 more source
Second generation antipsychotics causing neuroleptic malignant syndrome
Neuroleptic malignant syndrome (NMS) is a rare yet potentially lethal medical emergency encountered by psychiatrists. NMS is commonly associated with potent first generation antipsychotics, especially haloperidol and fluphenazine. However, there are many
C. Suraweera, R. Hanwella, V. De Silva
doaj +1 more source
Treatment decision-making capacity in children and adolescents hospitalized for an acute mental disorder: The role of cognitive functioning and psychiatric symptoms [PDF]
OBJECTIVE: This study was conducted to assess treatment decision-making capacity (TDMC) in a child and adolescent psychiatric sample and to verify possible associations between TDMC, psychiatric symptom severity, and cognitive functioning.
Ferracuti, Stefano +5 more
core +1 more source
Longitudinal Gut Microbiota Dysbiosis Underlies Olanzapine-Induced Weight Gain
Olanzapine is one of the most effective medicines available for stabilizing schizophrenia spectrum disorders. However, it has been reported to show the greatest propensity for inducing body weight gain and producing metabolic side effects, which cause a ...
Li Qian +10 more
doaj +1 more source

