Comparison of relapse rates of depot and oral antipsychotics in patients with schizophrenia [PDF]
Introduction: Antipsychotics are the mainstay of treatment in schizophrenia. First-generation and second-generation antipsychotics are available as oral and depot formulations.
Ball, Patrick +4 more
core +1 more source
Effect of melatonin in reducing second-generation antipsychotic metabolic effects: A double blind controlled clinical trial [PDF]
Introduction The use of second-generation atypical antipsychotics has an increasing role in the development of metabolic syndrome. However, these medications due to metabolic disorders can lead to an increased risk of cardiovascular disease and ...
Agahi, M. +4 more
core +1 more source
Antioxidant Properties of Second-Generation Antipsychotics: Focus on Microglia
Recent studies suggest a primary role of oxidative stress in an early phase of the pathogenesis of schizophrenia and a strong neurobiological link has been found between dopaminergic system dysfunction, microglia overactivation, and oxidative stress ...
Giuseppe Caruso +5 more
doaj +1 more source
Schizophrenia: Practical prescribing of antipsychotics [PDF]
Schizophrenia is commonly treated with antipsychotics. This article presents a major overview of prescribing antipsychotic for the non-medical prescriber.
Haygarth, Lynn, Hemingway, Steve
core +1 more source
Second generation antipsychotics causing neuroleptic malignant syndrome
Neuroleptic malignant syndrome (NMS) is a rare yet potentially lethal medical emergency encountered by psychiatrists. NMS is commonly associated with potent first generation antipsychotics, especially haloperidol and fluphenazine. However, there are many
C. Suraweera, R. Hanwella, V. De Silva
doaj +1 more source
How Quickly Do Physicians Adopt New Drugs? The Case of Second-Generation Antipsychotics [PDF]
Objective The authors examined physician adoption of second-generation antipsychotic medications and identified physician-level factors associated with early adoption. Methods The authors estimated Cox proportional-hazards models of time to adoption
Berndt, Ernst R. +5 more
core +1 more source
Treatment decision-making capacity in children and adolescents hospitalized for an acute mental disorder: The role of cognitive functioning and psychiatric symptoms [PDF]
OBJECTIVE: This study was conducted to assess treatment decision-making capacity (TDMC) in a child and adolescent psychiatric sample and to verify possible associations between TDMC, psychiatric symptom severity, and cognitive functioning.
Ferracuti, Stefano +5 more
core +1 more source
Objectives: The aim of this study was to determine the incidence of metabolic syndrome in patients treated with second-generation antipsychotics (SGAs).
Osama Abo Alrob +7 more
doaj +1 more source
Longitudinal Gut Microbiota Dysbiosis Underlies Olanzapine-Induced Weight Gain
Olanzapine is one of the most effective medicines available for stabilizing schizophrenia spectrum disorders. However, it has been reported to show the greatest propensity for inducing body weight gain and producing metabolic side effects, which cause a ...
Li Qian +10 more
doaj +1 more source
Rabbit syndrome: update on aetiology and management for pharmacists, psychiatrists and dentists [PDF]
Rabbit syndrome (RS) is an involuntary movement disorder, characterized by fast and fine movements of oral and masticatory muscles along the mouth vertical axis in the absence of tongue involvement.
Girgis, Eriny +2 more
core +1 more source

