Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Perampanel as a second-line therapy to midazolam reduces soman-induced status epilepticus and neurodegeneration in rats. [PDF]
Steier HG +8 more
europepmc +1 more source
Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky +5 more
wiley +1 more source
Lenvatinib as Second-Line Regimen after Atezolizumab plus Bevacizumab Combination Therapy
Masatoshi Kudo
doaj +1 more source
Conversion Liver Resection for Hepatocellular Carcinoma with Portal Vein Tumor Thrombus after Single Tremelimumab Regular Interval Durvalumab Regimen as a Second-Line Therapy: A Case Report. [PDF]
Akhmet D +14 more
europepmc +1 more source
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera +20 more
wiley +1 more source
Time-to-Event Modeling for Survival Prediction of Osimertinib as the First- and Second-Line Therapy. [PDF]
Lee S, Kim H, Lee H, Hahn J, Chang MJ.
europepmc +1 more source
Cadonilimab as second-line therapy in immunotherapy-resistant squamous NSCLC: a case report and review. [PDF]
Qiu S +5 more
europepmc +1 more source
High-Concentration Capsaicin Patch and Oral Pregabalin as Second-Line Therapy for Intercostobrachial Neuralgia After Breast Cancer Surgery: Open-Label Follow-Up of a Multicenter Randomized Controlled Clinical Trial. [PDF]
Dupoiron D +3 more
europepmc +1 more source
Brodalumab as a Second-Line Therapy in Psoriasis: Rapid Response and Unique Mechanism of Action After Biologic Failure. [PDF]
Green L, Armstrong A, Han G, Jacobson A.
europepmc +1 more source

