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Tegoprazan as First- and Second-Line Therapy for Eradication of Helicobacter pylori Infection: A Systematic Review and Meta-Analysis. [PDF]
Purja S, Lee Y, Kim E.
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Second-line cannabis therapy in patients with epilepsy
Clinical Neurology and Neurosurgery, 2023Marijuana-based therapies (MBTs) have been shown to reduce seizure frequency in patients with severe and drug-resistant epilepsy (DRE). Pharmaceutical-grade CBD (EpidiolexⓇ) was approved by the FDA in 2018 for the treatments of Dravet Syndrome (DS) and Lennox-Gastaut Syndrome (LGS) and subsequently in 2020 for tuberous sclerosis complex (TSC).
Erica, Braun +3 more
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Second-line therapy for esophageal cancer
Expert Review of Anticancer Therapy, 2007Esophageal cancer is a highly lethal disease, with most patients presenting with unresectable or metastatic disease. Since metastatic esophageal cancer is an incurable disease, the goals for chemotherapy are to palliate symptoms and improve survival.
Mike G, Martin +2 more
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Second-line therapy in bladder cancer
Current Opinion in Urology, 2009To review new developments in second-line treatment for transitional cell carcinoma of the urinary bladder focusing on advances and findings within the last year.So far no standard therapy has been established for pretreated patients with transitional cell carcinoma. Prognostic and predictive factors for response and outcome in pretreated patients have
Mark, Bachner, Maria, De Santis
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Second-Line Drug Therapy for Rheumatoid Arthritis
New England Journal of Medicine, 1994Three major classes of drugs are used in the treatment of patients with rheumatoid arthritis: nonsteroidal antiinflammatory drugs, corticosteroids, and drugs that are thought to modify fundamental pathologic processes responsible for the chronic inflammation.
Alastair J.J. Wood +2 more
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Second-Line Therapies in Metastatic Urothelial Carcinoma
Hematology/Oncology Clinics of North America, 2015Patients with relapsed or refractory urothelial carcinoma (UC) face a poor prognosis and a dearth of available treatment options that improve their survival. End-organ function and performance status play a vital role in the choice of second-line therapies.
Sujata, Narayanan +2 more
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A systematic review of second line therapies in toxic seizures
Clinical Toxicology, 2021Seizures are a common manifestation of toxic exposures requiring immediate and possibly ongoing management. Guidelines recommend benzodiazepines as first-line therapy for toxic seizures; however, there is a paucity of literature regarding optimal secondary treatment.
Meghan L. Fletcher +6 more
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Second-line and subsequent therapy for ovarian carcinoma
Current Oncology Reports, 2002Ovarian carcinoma continues to be the leading cause of death among gynecologic malignancies. Paclitaxel and platinum chemotherapy is still the treatment of choice after primary debulking surgery. Salvage chemotherapy with several single agents has only modest activity and does not prolong survival of patients with relapsed ovarian carcinoma. An intense
Prema P, Peethambaram, Harry J, Long
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