Results 251 to 260 of about 13,963,189 (308)

Second-line cannabis therapy in patients with epilepsy

Clinical Neurology and Neurosurgery, 2023
Marijuana-based therapies (MBTs) have been shown to reduce seizure frequency in patients with severe and drug-resistant epilepsy (DRE). Pharmaceutical-grade CBD (EpidiolexⓇ) was approved by the FDA in 2018 for the treatments of Dravet Syndrome (DS) and Lennox-Gastaut Syndrome (LGS) and subsequently in 2020 for tuberous sclerosis complex (TSC).
Erica, Braun   +3 more
openaire   +2 more sources

Second-line therapy for esophageal cancer

Expert Review of Anticancer Therapy, 2007
Esophageal cancer is a highly lethal disease, with most patients presenting with unresectable or metastatic disease. Since metastatic esophageal cancer is an incurable disease, the goals for chemotherapy are to palliate symptoms and improve survival.
Mike G, Martin   +2 more
openaire   +2 more sources

Second-line therapy in bladder cancer

Current Opinion in Urology, 2009
To review new developments in second-line treatment for transitional cell carcinoma of the urinary bladder focusing on advances and findings within the last year.So far no standard therapy has been established for pretreated patients with transitional cell carcinoma. Prognostic and predictive factors for response and outcome in pretreated patients have
Mark, Bachner, Maria, De Santis
openaire   +2 more sources

Second-Line Drug Therapy for Rheumatoid Arthritis

New England Journal of Medicine, 1994
Three major classes of drugs are used in the treatment of patients with rheumatoid arthritis: nonsteroidal antiinflammatory drugs, corticosteroids, and drugs that are thought to modify fundamental pathologic processes responsible for the chronic inflammation.
Alastair J.J. Wood   +2 more
openaire   +2 more sources

Second-Line Therapies in Metastatic Urothelial Carcinoma

Hematology/Oncology Clinics of North America, 2015
Patients with relapsed or refractory urothelial carcinoma (UC) face a poor prognosis and a dearth of available treatment options that improve their survival. End-organ function and performance status play a vital role in the choice of second-line therapies.
Sujata, Narayanan   +2 more
openaire   +2 more sources

A systematic review of second line therapies in toxic seizures

Clinical Toxicology, 2021
Seizures are a common manifestation of toxic exposures requiring immediate and possibly ongoing management. Guidelines recommend benzodiazepines as first-line therapy for toxic seizures; however, there is a paucity of literature regarding optimal secondary treatment.
Meghan L. Fletcher   +6 more
openaire   +2 more sources

Second-line and subsequent therapy for ovarian carcinoma

Current Oncology Reports, 2002
Ovarian carcinoma continues to be the leading cause of death among gynecologic malignancies. Paclitaxel and platinum chemotherapy is still the treatment of choice after primary debulking surgery. Salvage chemotherapy with several single agents has only modest activity and does not prolong survival of patients with relapsed ovarian carcinoma. An intense
Prema P, Peethambaram, Harry J, Long
openaire   +2 more sources

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