Results 51 to 60 of about 13,963,189 (308)

Treatment sequences of patients with advanced colorectal cancer and use of second-line FOLFIRI with antiangiogenic drugs in Japan: A retrospective observational study using an administrative database.

PLoS ONE, 2021
The objectives were to describe treatment sequences for advanced colorectal cancer (CRC), use of second-line FOLFIRI (leucovorin, 5-fluorouracil, irinotecan) plus antiangiogenic drug (bevacizumab, ramucirumab, aflibercept beta) therapy, and the factors ...
Eiji Shinozaki, Akitaka Makiyama, Yoshinori Kagawa, Hironaga Satake, Yoshinori Tanizawa, Zhihong Cai, Yongzhe Piao   +6 more
doaj   +1 more source

Comparison of endocrine therapy and chemotherapy as different systemic treatment modes for metastatic luminal HER2-negative breast cancer patients —A retrospective study

Frontiers in Oncology, 2022
PurposeThe purpose of this study was to evaluate endocrine therapy and chemotherapy for first-line, maintenance, and second-line treatment of hormone receptor-positive HER-2-negative metastatic breast cancer (HR+HER-2-MBC) and the relationship between ...
Qiuyue Liu, Juan Qiu, Qianrun Lu, Yujin Ma, Shu Fang, Bing Bu, Lihua Song   +6 more
doaj   +1 more source

Methotrexate vs Azathioprine in Second-line Therapy of Sarcoidosis [PDF]

Chest, 2013
Steroids remain the first-choice therapeutic in sarcoidosis; however, long-term use is associated with toxicity. Evidence defining the best second-line therapeutic is currently lacking. The aim of this study was to compare the effect of methotrexate and azathioprine on prednisone tapering, pulmonary function, and side effects in the second-line ...
Vorselaars, Adriane D. M., Wuyts, Wim A., Vorselaars, Veronique M. M., Zanen, Pieter, Deneer, Vera H. M., Veltkamp, Marcel, Thomeer, Michiel, van Moorsel, Coline H. M., Grutters, Jan C.   +8 more
openaire   +3 more sources

Clinical and Pathological Characteristics of Metastatic Renal Cell Carcinoma Patients Needing a Second-Line Therapy: A Systematic Review

, 2020
A high percentage of patients with metastatic renal cell carcinoma (mRCC) require a second-line option. We aimed to summarize available evidences about the clinicopathological profile of mRCC patients who receive a second-line therapy.
Marco Capece, Capece, Marco, Roberto La Rocca, Mangiapia, Francesco, Mirone, Vincenzo, Napolitano, Luigi, Nicola Longo, Buonerba, Carlo, La Rocca, Roberto, Creta, Massimiliano, Califano, Gianluigi, Carlo Buonerba, Fabio Esposito, Francesco Mangiapia, Fusco, Ferdinando, Claudia Collà Ruvolo, Massimiliano Creta, Ferdinando Fusco, Collà Ruvolo, Claudia, Giuseppe Celentano, Esposito, Fabio, Celentano, Giuseppe, Vincenzo Mirone, Longo, Nicola, Gianluigi Califano, Luigi Napolitano   +25 more
core   +1 more source

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source

Efficacy and safety of second-line cabozantinib after immuno-oncology combination therapy for advanced renal cell carcinoma: Japanese multicenter retrospective study

Scientific Reports, 2023
Immuno-oncology (IO) combination therapy is utilized as a first-line systemic treatment for advanced renal cell carcinoma. However, evidence supporting the use of cabozantinib after IO combination therapy is lacking.
Tomokazu Sazuka, Yuto Matsushita, Hiroaki Sato, Takahiro Osawa, Nobuyuki Hinata, Shingo Hatakeyama, Kazuyuki Numakura, Kosuke Ueda, Takahiro Kimura, Masayuki Takahashi, Hajime Tanaka, Yoshihide Kawasaki, Toshifumi Kurahashi, Takuma Kato, Kazutoshi Fujita, Makito Miyake, Takahiro Kojima, Hiroshi Kitamura, Hideaki Miyake, Tomohiko Ichikawa   +19 more
doaj   +1 more source

Tenofovir in second-line ART in Zambia and South Africa: collaborative analysis of cohort studies. [PDF]

, 2012
Article approval pendingTenofovir (TDF) is increasingly used in second-line antiretroviral treatment (ART) in sub-Saharan Africa. We compared outcomes of second-line ART containing and not containing TDF in cohort studies from Zambia and the Republic of ...
Brennan, Alana, Olivia Keiser, Cleophas Chimbetete, Lloyd Mulenga, Giddy, Janet, Egger, Matthias, Hans Prozesky, Janet Giddy, Wandeler, Gilles, Alana Brennan, Christopher J. Hoffmann, Robin Wood, Thom Chaweza, Chaweza, Thom, Daniela Garone, Gilles Wandeler, Matthias Egger, Keiser, Olivia, Mulenga, Lloyd, Hoffmann, Christopher J, Chimbetete, Cleophas, Prozesky, Hans, Boulle, Andrew, Garone, Daniela, IeDEA Southern Africa Collaboration,, Andrew Boulle, Wood, Robin, Egger M, Wandeler G, Giddy J, Hoffmann CJ, Chimbetete C, Garone D, Chaweza T, Mulenga L, Boulle A, Brennan A, Prozesky H, Wood R, Keiser O   +39 more
core   +3 more sources

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Retrospective analysis of the clinical and demographic variables on the outcomes after second-line treatment in advanced non-small cell lung cancer

Indian Journal of Medical and Paediatric Oncology, 2013
Background: Platinum based doublets chemotherapy are the standard of care for metastatic or advanced non-small cell lung carcinoma. This leads to modest survival advantage and improve quality-of-life. However, patients with advanced or metastatic disease
Sourav Sau, Anirban Biswas, Amitava Roy, Saikat Sau, Subir Ganguly   +4 more
doaj   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source