Results 31 to 40 of about 13,963,189 (308)

Treatment failure and mortality factors in patients receiving second-line HIV therapy in resource-limited countries. [PDF]

open access: yes, 2010
To view this article, click on "Additional Links".CONTEXT: Long-term antiretroviral therapy (ART) use in resource-limited countries leads to increasing numbers of patients with HIV taking second-line therapy. Limited access to further therapeutic options
Mar Pujades-Rodríguez   +6 more
core   +1 more source

Second line anti-cancer therapy for metastatic colorectal cancer: treatment strategy

open access: yesМедицинский совет, 2015
Colorectal cancer is one of the most widespread cancers globally. Over the past decade, there has been a significant progress in the treatment of metastatic colorectal cancer.
K. A. Vorontsova   +2 more
doaj   +1 more source

Efficacy of Twice a Day Bismuth Quadruple Therapy for Second-Line Treatment of Helicobacter pylori Infection

open access: yes, 2022
Bismuth quadruple therapy (BQT) is an effective treatment for Helicobacter pylori infection. However, frequent dosing schedules of BQT regimen often compromise drug adherence and may affect treatment outcomes.
Woo Jin Jeong   +9 more
core   +1 more source

Second-Line Therapy Tyrosine Kinase Inhibitor for Chronic Phase Chronic Myeloid Leukemia Resistant to Imatinib [PDF]

open access: yes, 2022
Since the era of tyrosine kinase inhibitor (TKI) therapy, there has been an increase in the median survival of chronic myeloid leukemia. Nevertheless, nowadays there were several cases of chronic myeloid leukemia that are resistant to the first-line TKIs,
Pratiwi, Chici   +3 more
core   +1 more source

Consequences of targeted treatments for second-line therapy

open access: yesAnnals of Oncology, 2010
The paradigm for first-line treatment of relapsed or metastatic non-small cell lung cancer (NSCLC) is changing. Large phase III trials demonstrated that, in 2010, we cannot select a therapy without an accurate definition of tumor histology and epidermal growth factor receptor (EGFR) status.
E, De Maio   +10 more
openaire   +2 more sources

Immunomodulatory Second-Line Therapies for Immune Thrombocytopenia [PDF]

open access: yesHämostaseologie, 2019
AbstractManagement of immune thrombocytopenia (ITP) is complex requiring communication between patients and caregivers to establish a mutual understanding of the impact of the patient's disease on quality of life, the current symptoms and risk of morbidity/mortality and the goals of therapy. The currently available second-line therapies for ITP provide
openaire   +2 more sources

New cross-roads for second line medical therapy in acromegaly [PDF]

open access: yesArchives of the Balkan Medical Union, 2018
Acromegaly is a complex disorder caused by growth hormone excess mostly due to a pituitary adenoma. Surgery represents the first option but rate of long time success is almost 50% thus the patients need other therapies.
Adina Ghemigian   +5 more
doaj  

HIV-1 Drug Resistance and Third-Line Therapy Outcomes in Patients Failing Second-Line Therapy in Zimbabwe. [PDF]

open access: yes, 2018
Objectives To analyze the patterns and risk factors of HIV drug resistance mutations among patients failing second-line treatment and to describe early treatment responses to recommended third-line antiretroviral therapy (ART) in a national referral ...
Cleophas Chimbetete   +14 more
core   +2 more sources

Real-world outcomes in patients with first-line and second-line therapy for advanced esophageal squamous cell carcinoma Supplementary Tables

open access: yes, 2023
Real-world outcomes in patients with first-line and second-line therapy for advanced esophageal squamous cell carcinoma Supplementary Tables 
Naomi Sacks (14515044)   +5 more
core   +1 more source

Efficacy and safety of abemaciclib alone and with PI3K/mTOR inhibitor LY3023414 or galunisertib versus chemotherapy in previously treated metastatic pancreatic adenocarcinoma: A randomized controlled trial

open access: yesCancer Medicine, 2023
Background Pancreatic ductal adenocarcinomas (PDAC) are characterized by frequent cell cycle pathways aberrations. This study evaluated safety and efficacy of abemaciclib, a cyclin‐dependent kinase 4 and 6 inhibitor, as monotherapy or in combination with
E. Gabriela Chiorean   +11 more
doaj   +1 more source

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