Results 71 to 80 of about 4,270,653 (326)
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
SECOND ORDER OPTIMALITY CONDITIONS
Doklady Belorusskogo gosudarstvennogo universiteta informatiki i radioèlektroniki, 2019 Nonlinear programming problems are studied. Necessary second order optimality conditions are proved under minimal assumptions about constraints.
A. E. Leschov, L. I. Minchenko
doaj
Second-order nonlinear neutral differential equations with delay term: Novel oscillation theorems
AIMS MathematicsThis work aims to propose novel criteria to guarantee the oscillation of solutions for second-order differential equations. To analyze the oscillatory characteristics of the studied equation, new necessary conditions are introduced.
Saeed Althubiti
doaj +1 more source
Oscillation result for half-linear delay difference equations of second-order
Mathematical Biosciences and Engineering, 2022 In this paper, we obtain the new single-condition criteria for the oscillation of second-order half-linear delay difference equation. Even in the linear case, the sharp result is new and, to our knowledge, improves all previous results.
Chinnasamy Jayakumar +6 more
doaj +1 more source
Second-Order Agents on Ring Digraphs
, 2018 The paper addresses the problem of consensus seeking among second-order linear agents interconnected in a specific ring topology. Unlike the existing results in the field dealing with one-directional digraphs arising in various cyclic pursuit algorithms ...
Chebotarev, Pavel, Parsegov, Sergei
core +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Fracture and second-order phase transitions
, 2000 Using the global fiber bundle model as a tractable scheme of progressive fracture in heterogeneous materials, we define the branching ratio in avalanches as a suitable order parameter to clarify the order of the phase transition occurring at the collapse
Gomez, J. B., Moreno, Y., Pacheco, A. F.
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Witnessing Entanglement with Second-Order Interference
, 2006 Second-order interference and Hanbury-Brown and Twiss type experiments can provide an operational framework for the construction of witness operators that can test classical and nonclassical properties of a Gaussian squeezed state (GSS), and provide ...
B. Yurke +4 more
core +1 more source
Affine connections and second-order affine structures
, 2020 Smooth manifolds have been always understood intuitively as spaces with an affine geometry on the infinitesimal scale. In Synthetic Differential Geometry this can be made precise by showing that a smooth manifold carries a natural structure of an ...
Bár, Filip
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