Results 41 to 50 of about 195,148 (324)
Abstract and Applied Analysis, 2011 Some new properties are obtained for generalized second-order contingent (adjacent) epiderivatives of set-valued maps. By employing the generalized second-order adjacent epiderivatives, necessary and sufficient conditions of Benson proper efficient ...
Qilin Wang, Guolin Yu
doaj +1 more source
, 2014 In this paper, we introduce a new second-order directional derivative and a second-order subdifferential of Hadamard type for an arbitrary nondifferentiable function.
Ivanov, Vsevolod I.
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
On generalized derivatives for C1,1 vector optimization problems
Journal of Applied Mathematics, 2003 We introduce generalized definitions of Peano and Riemann directional derivatives in order to obtain second-order optimality conditions for vector optimization problems involving C1,1 data.
Davide La Torre
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Trends in Computational and Applied Mathematics, 2019 First and second order necessary optimality conditions of Karush-Kuhn-Tucker type are established for continuous-time optimization problems with equality and inequality constraints.
Moisés Rodrigues Cirilo Monte +1 more
doaj +1 more source
$L^1$-optimality conditions for circular restricted three-body problems
, 2015 In this paper, the L1-minimization for the translational motion of a spacecraft in a circular restricted three-body problem (CRTBP) is considered. Necessary con- ditions are derived by using the Pontryagin Maximum Principle, revealing the existence of ...
Chen, Zheng
core +3 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Second order optimality conditions for infinite programs [PDF]
, 1989 The paper deals with the minimization problem of a marginal function over a subset C of a space X. Unlike the existing papers, X is not assumed to be a finitedimensional space and C is a geometric constraint which may not coincide with X.
Oettli, Werner, Sach, Pham H.
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source