Results 81 to 90 of about 2,352,988 (278)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The fish in the creek is sentient, even if I can’t speak with it

open access: yesTrans/Form/Ação
: In this paper I argue that Velmens’ reflexive model of perceptual consciousness is useful for understanding the first-person perspective and sentience in animals.
Michael L. Woodruff
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Justice, Claims and Prioritarianism: Room for Desert? [PDF]

open access: yes, 2016
Does individual desert matter for distributive justice? Is it relevant, for purposes of justice, that the pattern of distribution of justice’s “currency” (be it well-being, resources, preference-satisfaction, capabilities, or something else) is aligned ...
Adler, Matthew D.
core   +2 more sources

Resoundings of the flesh: Caring for others by way of “second person” perspectivity

open access: yesInternational Journal of Qualitative Studies on Health and Well-being, 2012
In bringing ourselves to the encounter with the experience of others, we bring our bodies with us-and, in doing so, we are able to resonate not only intellectually but also empathically with the other's experiences and expressions (which are given to us both verbally and nonverbally).
openaire   +3 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

What I Can Do with the Right Version of You: The Impact of Narrative Perspective on Reader Immersion, and How (in)Formal Address Pronouns Influence Immersion Reports

open access: yesLanguages
Previous research has shown that readers experience stronger immersion while reading first-person narratives than third-person narratives, but whether this difference in processing is time-sensitive remains unclear.
Patricia Sánchez Carrasco   +2 more
doaj   +1 more source

Syarat Kesehatan Fisik Bagi Calon Presiden dalam Perspektif Politik Islam dan Politik Indonesia

open access: yesAhkam: Jurnal Ilmu Syariah, 2017
This article specifically discusses the important issues on physical health requirements for presidential candidates in Islamic and Indonesian perspectives.
Mujar Ibnu Syarif
doaj   +1 more source

Exploring content and psychometric validity of newly developed assessment tools for itch and skin pain in atopic dermatitis. [PDF]

open access: yes, 2019
BackgroundAtopic dermatitis (AD) is a common skin disorder characterized by chronic inflammation, altered skin barrier function, and inflammatory cell skin infiltration that decreases health-related quality of life (HRQoL).
Abetz-Webb, Linda   +11 more
core  

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