Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Experimental and theoretical study of second and third harmonic generation in amorphous silicon
We report contrasted experimental and theoretical results on second and third harmonic generation from an amorphous silicon nanolayer. We perform this study by analysing the harmonic optical signals generated when fs and ps pulses tuned at 800nm and ...
Scalora, Michael +5 more
core +1 more source
Frequency comb generation threshold via second-harmonic excitation in χ(2) optical microresonators
We investigate the threshold of χ(2) frequency comb generation in lithium niobate whispering gallery microresonators theoretically and experimentally. When generating a frequency comb via second-harmonic excitation, also commonly known as second-harmonic
Jan Szabados +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Random Quasi-Phase-Matched Second Harmonic Generation in Periodically Poled Lithium Tantalate
We experimentally observed and explained bulk second harmonic generation via random quasi-phase-matching, derived from a periodically poled lithium tantalate sample with a randomly patterned mark-to-space ...
A. Pasquazi +13 more
core +1 more source
Second harmonic generation at a time-varying interface
Time-varying metamaterials rely on large and fast changes of the linear permittivity. Beyond the linear terms, however, the effect of a non-perturbative modulation of the medium on harmonic generation remains largely unexplored.
Romain Tirole +8 more
doaj +1 more source
Optical Second Harmonic Generation of Low-Dimensional Semiconductor Materials
In recent years, the phenomenon of optical second harmonic generation (SHG) has attracted significant attention as a pivotal nonlinear optical effect in research. Notably, in low-dimensional materials (LDMs), SHG detection has become an instrumental tool
Yue Fu +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Conservation laws of generalized angular momentum by second-harmonic generation in underdense plasmas harmonic generation [PDF]
Light beams exhibit two intrinsic quantized degrees of freedom: spin angular momentum (SAM) and orbital angular momentum (OAM) whose manipulation enables precise control over the topological characteristics of electromagnetic fields. Recently, structured
Voisine Alexis +5 more
doaj +1 more source
Second-harmonic generation of temporally low-coherence light
In this Letter, we study the second-harmonic (SH) generation of temporally low-coherence light using the statistical optics method. By introducing the statistical characteristics of low-coherence light into the nonlinear coupled wave equation, we predict
Xiaohui Zhao +11 more
doaj +1 more source

