Results 61 to 70 of about 10,174,341 (277)

Second language learners’ achievement in literature through problem-based learning method

Journal of the Scholarship of Teaching and Learning, 2012
Teaching literature to L2 learners demands methodological training and innovative strategies to bring effectiveness in learning. Problem based instructional strategy is being widely used to determine its impact on learner’s achievement, retention ...
Muhammad Athar Hussain, Muhammad Nafees, Nabi Bux Jumani   +2 more
doaj  

Foreign language comprehension achievement: insights from the cognate facilitation effect

Frontiers in Psychology, 2015
Numerous studies have shown that the native language influences foreign word recognition and that this influence is modulated by the proficiency in the nonnative language.
Aina eCasaponsa, Eneko eAntón, Alejandro ePérez, Jon Andoni eDunabeitia   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

The Immersion Centre and the Dual-Track School: A Study of the Relationship between School Environment and Achievement in a French Immersion Program

Canadian Journal of Education, 1981
Now that the early French-immersion program is a well-established educational alternative for English-speaking students in the Carleton Board of Education in Ontario, it has become important to examine factors which may influence the achievement of ...
Sharon Lapkin , Christine M. Andrew , Birgit Harley, Merrill Swain , Jill Kamin   +4 more
doaj  

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Using Questionnaires to Assess Motivation in Second Language Classrooms [PDF]

, 1996
Questionnaires for measuring motivation and attitudes in second language (SL) learning can be adapted from existing instruments or they can be constructed for use in other contexts.
O'Bryen, Patricia
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Implicit Knowledge, Explicit Knowledge, and Achievement in Second Language (L2) Spanish

Canadian Journal of Applied Linguistics, 2012
Implicit and explicit knowledge of the second language (L2) are two central constructs in the field of second language acquisition (SLA). In recent years, there has been a renewed interest in obtaining valid and reliable measures of L2 learners ...
Xavier Gutiérrez
doaj