Results 61 to 70 of about 1,146,237 (234)
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Theoretical syntax in second language acquisition research and in second language classroom research
Stellenbosch Papers in Linguistics Plus, 2014 No abstract available.
openaire +3 more sources
LEXTALE_CH: A quick, character-based proficiency test for Mandarin Chinese [PDF]
, 2018 Research in second language acquisition suggests that objective performance-based assessments may provide more reliable and valid measures of second language proficiency than subjective self-ratings. To measure proficiency in English as a second language,
Chan, I. Lei, Chang, Charles B.
core
Network Localization of Fatigue in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source
Situating Grammar Instruction in the World Language Classroom: Four Content-Enriched Strategies [PDF]
, 2009 The role of grammar instruction in promoting communicative competence continues to be a controversial issue for the world language classroom teacher. Second language acquisition research suggests that critical to sustained progress in language use is a ...
Hernández, Todd A.
core +1 more source
Native Language (L1) Transfer in Second Language Learning: From Form to Concept, the Implications [PDF]
, 2017 The influence that a student’s first language (L1) can have on their acquisition of a second language (L2) has been frequently noted by language teachers (Swan, 1997; Jarvis, 2007) and documented in the literature for decades.
Austen, Samantha
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Teaching Authentic English Pronounciation [PDF]
, 2011 Most of the evidence from different research and literature indicates that learners beyond the age of puberty cannot acquire authentic pronunciation of a second language, because the articulation muscles have already lost their flexibility to be able to ...
Rashtchi, Mehrdad
core
Age effects in first language attrition: speech perception by Korean-English bilinguals [PDF]
, 2017 This article has been awarded Open Materials and Open Data badges. All materials and data are publicly accessible via the Open Science Framework at https://osf.io/B2478 and at https://osf.io/G4C7Z.
Ahn, Sunyoung +3 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein +7 more
wiley +1 more source