Results 51 to 60 of about 10,982,257 (285)

Applied Sociolinguistics: The Case of Arabic as a Second Language [PDF]

open access: yes, 1986
This paper has several themes. The first is that almost everything that sociolinguists can discover about the sociolinguistic patterning of Arabic will have some relevance for the teaching and learning of Arabic as a second language.
Schmidt, Richard W.
core   +1 more source

COMMENTARY: CAN FREE READING TAKE YOU ALL THE WAY? A RESPONSE TO COBB (2007) [PDF]

open access: yesLanguage Learning and Technology, 2008
Cobb (2007) argues that free reading cannot provide L2 readers with sufficient opportunities for acquiring vocabulary in order to reach an adequate level of reading comprehension of English texts.
Jeff McQuillan, Stephen D. Krashen
doaj  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Contradictions within an activity of second language reading literacy

open access: yesSouth African Journal of Childhood Education, 2019
Background: In investigating the early reading literacy of a group of Setswana-speaking children who learnt to read in Afrikaans, cultural historical activity theory (CHAT) was chosen as a conceptual framework because of its proven utility value in ...
Sonja Brink, Carisma Nel
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

Second Language Reading Research and Instruction: Crossing the Boundaries

open access: yesStudies in Applied Linguistics & TESOL, 2010
Second language (L2) reading serves dual roles in L2 learning – both as a literacy skill for comprehension and as a source of L2 input (Eskey, 2005; Grabe, 1991).
Jookyoung Jung
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

COMMENTARY: RESPONSE TO MCQUILLAN AND KRASHEN (2008) [PDF]

open access: yesLanguage Learning and Technology, 2008
I was glad to receive a response from Jeff McQuillan and Stephen Krashen to my piece "Computing the Demands of Vocabulary Acquisition from Reading" (Language Learning & Technology, October, 2007), because drafting a reply forces me to be even more clear ...
Tom Cobb
doaj  

Second Language Reading Research and Instruction: Crossing the Boundaries

open access: yesWorking Papers in Applied Linguistics and TESOL, 2015
Second language (L2) reading serves dual roles in L2 learning – both as a literacy skill for comprehension and as a source of L2 input (Eskey, 2005; Grabe, 1991).
Jookyoung Jung
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

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