Results 101 to 110 of about 13,925,210 (307)
Medication beliefs in first-line and second-line treated multiple sclerosis patients
, 2020 Background: Immune treatments of multiple sclerosis (MS) can be classified in first-line and second-line approaches. While in both treatment efficacy is often not easy to assess in the short-term, treatment and illness beliefs may differ in first-line ...
Weierstall-Pust, Roland +6 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
STUDY ON INCREASING THE EFFICIENCY IN VOLLEYBALL
Studia Universitatis Babeş-Bolyai: Educatio Artis Gymnasticae, 2016 Starting from the analysis of the current global performance context in volleyball and our internal realities, we consider it appropriate to conceptually address the optimization strategy of the Romanian volleyball performance, by comparing the results ...
Florin ȚURCANU, Dana Simona ȚURCANU
doaj +2 more sources
Second-Line Treatment Options for Hepatocellular Carcinoma: Current Landscape and Future Direction
Journal of Hepatocellular Carcinoma, 2021 Surabhi Pathak,1 Mohamad Bassam Sonbol2 1Hematology-Oncology, King’s Daughters Medical Center, Ashland, KY, USA; 2Division of Hematology/Oncology, Department of Internal Medicine, Mayo Clinic Cancer Center, Phoenix, AZ, USACorrespondence: Mohamad Bassam ...
Pathak S, Sonbol MB
doaj
Second-line systemic treatment for advanced cholangiocarcinoma.
, 2014 371 Background: Five-year survival for advanced cholangiocarcinoma (aCC) is reported at 5-10%. For advanced, unresectable patients, gemcitabine plus platinum (GEM-P) combination chemotherapy is common practice as first-line treatment with progression ...
Ahmed Omar Kaseb +6 more
core +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Lung Cancer: Targets and TherapyJoo Sung Shim,1 Youhyun Kim,1 Taeho Yuh,1 Jii Bum Lee,2 Hye Ryun Kim,2 Min Hee Hong,2 Byoung Chul Cho,2 Sun Min Lim2 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea; 2Division of Medical Oncology ...
Shim JS +7 more
doaj
The Pan African Medical Journal, 2019 INTRODUCTION: Mortality of adult patients who are on antiretroviral therapy (ART) is higher in low-income than in high-income countries. After the failure of standard first-line treatment, patients switch to second-line regimens.
Adino Tesfahun Tsegaye +2 more
doaj +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source