Results 121 to 130 of about 1,581,172 (300)

Second primary cancers among 109 000 cases of non-Hodgkin's lymphoma [PDF]

, 2005
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldAn analysis of other primary cancers in individuals with non-Hodgkin's lymphoma (NHL) can help to elucidate this cancer aetiology.
A Andersen, Martos, C, Kliewer, E. V., Andersen, A., D H Brewster, A Seow, D Colin, E Pukkala, Hemminki, K, G Scélo, Pompe-Kirn, V, K Hemminki, Colin, D., Tonita, J M, Brewster, D. H., Pukkala, E., McBride, M. L., Boffetta, P., Andersen, A, Hemminki, K., Colin, D, P Boffetta, M L McBride, E V Kliewer, Jonasson, J G, Tonita, J. V., Brennan, P., Pukkala, E, Seow, A., P Brennan, J M Tonita, Brennan, P, Boffetta, P, Pompe-Kirn, V., V Pompe-Kirn, Scélo, G., Scélo, G, Seow, A, Mellemkjaer, L, Jonasson, J. G., Brewster, D H, McBride, M L, Martos, C., Kliewer, E V, E Tracey, J G Jonasson, Tracey, E, C Martos, Tracey, E., Mellemkjaer, L., L Mellemkjaer   +50 more
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Breast cancer and second primary ovarian cancer in dermatomyositis

Gynecologic Oncology, 1991
We report six female patients with breast cancer who developed dermatomyositis and compare our data with those from other reports. The development of dermatomyositis in two patients led to the discovery of a second primary ovarian carcinoma, whereas the development of dermatomyositis in another two patients led to the discovery of recurrent breast ...
Voravud, Narin, Dimopoulos, Meletios, Hortobagyi, Gabriel, Ross, Merrick, Theriault, Richard   +4 more
openaire   +4 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Family History and Risk of Second Primary Breast Cancer after In Situ Breast Carcinoma [PDF]

, 2018
Background: Incidence rates of in situ breast carcinomas have increased due to widespread adoption of mammography. Very little is known about why some women with in situ breast cancer later develop second primary breast cancers.
Kathleen E. Malone, Peggy Porter, Christopher I. Li, Mei-Tzu C. Tang, Michelle L. Baglia   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Lifelong cancer incidence in 47,697 patients treated for childhood cancer in the Nordic countries. [PDF]

, 2009
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldBACKGROUND: The pattern of cancer in long-term survivors from childhood cancer has not been investigated comprehensively. METHODS: We obtained a
Anderson, Harald, Rechnitzer, Catherine, Garwicz, Stanislaw, Garwicz, Stanislaw,, Olsen, Hans Jørgen Holde, Olsen, Jørgen H, Langmark, Frøydis, Anderson, Harald,, Tryggvadottír, Laufey, Möller, Torgil,, Jonmundsson, Gudmundur, Möller, Torgil, Sankila, Risto, Lund University., Christensen, Jane, Winther, Jeanette Falck   +15 more
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High incidence of lung cancer death after curative endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma

Cancer Medicine
Background and Aim Following treatment of superficial esophageal squamous cell carcinoma (ESCC), surveillance for a second primary malignancy (SPM) is necessary. However, detailed evidence regarding the timing and prognosis of SPMs is insufficient.
Ayaka Tajiri, Yoshiki Tsujii, Tsutomu Nishida, Takuya Inoue, Akira Maekawa, Shinji Kitamura, Shinjiro Yamaguchi, Akihiro Nishihara, Takuya Yamada, Hideharu Ogiyama, Yoko Murayama, Shunsuke Yamamoto, Satoshi Egawa, Ryotaro Uema, Takeo Yoshihara, Yoshito Hayashi, Tetsuo Takehara   +16 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Second Primary Lung Cancer: A Current Problem in Long-Survivor Cancer Patients [PDF]

, 2016
Background: Lung may be the site of synchronous or metachronous second primary malignancies (SPM) with an incidence between 0.8 and 14.5% of cases. Synchronous or metachronous SPM present, however, diagnostic and therapeutic challenges.
MUCILLI, Felice, Barone, Mirko, Guetti, Luigi, Sacco, Rosario, Di Nuzzo, Decio, Camplese, Pierpaolo, Cipollone, Giuseppe, Ippoliti, Massimo, Prioletta, Marko, Rizzuto, Antonia   +9 more
core  

Primary and secondary prevention of breast cancer [PDF]

, 2017
Introduction Breast cancer is the most common cancer among women and is the second cancer frequently occurring worldwide of newly-diagnosed cancers. There is much evidence showing the influence of life style and environmental factors on the development ...
Franciszek Burdan, Kukiełka-Budny, Bożena, Agnieszka Budny, Agnieszka Kolak, Burdan, Franciszek, Dariusz Surdyka, Surdyka, Dariusz, Sygit, Katarzyna, Budny, Agnieszka, Kolak, Agnieszka, Kamińska, Marzena, Bożena Kukiełka-Budny, Marzena Kamińska, Katarzyna Sygit   +13 more
core   +1 more source