Results 131 to 140 of about 14,604,770 (257)

Risk of second primary cancers in women diagnosed with endometrial cancer in German and Swedish cancer registries

open access: yes, 2017
Along with the increasing incidence and favorable prognosis, more women diagnosed with endometrial cancer may develop second primary cancers (SPCs). We aimed at investigating risk of SPCs after endometrial cancer in Germany and Sweden to provide insight ...
Kari Hemminki   +41 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Cancer Trends: non-Hodgkin’s lymphoma (NHL)

open access: yes, 2013
An average of 660 cases of non Hodgkin’s lymphoma (NHL) was diagnosed per year in Ireland between 2007 and 2011 (Table 1). Incidence rates were slightly higher in males than in females where NHL was the 5th and 8th most common cancer diagnosed ...
National Cancer Registry Ireland (NCRI)
core  

Suicide rates among patients with first and second primary cancer. [PDF]

open access: yesEpidemiol Psychiatr Sci, 2023
Jiang Y   +10 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Second primary cancers in people who had cancer as children: an Australian Childhood Cancer Registry population-based study

open access: yes, 2019
Objective: To investigate the incidence of second primary cancers in people diagnosed with cancer during childhood. Design, setting: Retrospective, population-based study; analysis of Australian Childhood Cancer Registry data.
Baade, Peter D.   +11 more
core   +1 more source

Incidence Differences Between First Primary Cancers and Second Primary Cancers Following Skin Squamous Cell Carcinoma as Etiological Clues

open access: yesClinical Epidemiology, 2020
Guoqiao Zheng,1– 3 Kristina Sundquist,4– 6 Jan Sundquist,4– 6 Asta Försti,1,4,7,8 Akseli Hemminki,9,10 Kari Hemminki1,2,4,11 1Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg D-69120 ...
Zheng G   +5 more
doaj  

The risk of second primary cancer after nasopharyngeal cancer: a systematic review. [PDF]

open access: yesEur Arch Otorhinolaryngol, 2023
Svärd F   +4 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Cancer Trends: skin cancers [PDF]

open access: yes, 2017
Skin cancers are the most commonly diagnosed cancers among Caucasian populations with ultra violet radiation (UVR) the most well documented risk factor.
National Cancer Registry Ireland (NCRI)
core  

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