Results 61 to 70 of about 1,581,172 (300)

High constant incidence of second primary colorectal cancer [PDF]

, 2013
Patients who had a colorectal cancer have a 1.5- to 2-fold excess risk of a second colorectal cancer as compared to the general population, the excess being higher at younger age at diagnosis.
La Vecchia, Carlo, M. Maspoli Conconi, C. Bosetti, L. Randimbison, Rosato, Valentina, Randimbison, Lalao, Maspoli-Conconi, Manuela, V. Rosato, Levi, Fabio, C. La Vecchia, Blanc-Moya, Rafael, R. Blanc Moya, F. Levi, Bosetti, Cristina   +13 more
core   +1 more source

Clinical characteristics of second primary pancreatic cancer.

PLoS ONE, 2017
PurposeSeveral studies reported the increased risk of second primary pancreatic ductal adenocarcinoma (2nd PDAC) in cancer survivors. However, data on the characteristics of 2nd PDAC are insufficient.MethodsThis retrospective cohort study included 1759 ...
Jung Hyun Jo, In Rae Cho, Jang Han Jung, Hee Seung Lee, Moon Jae Chung, Seungmin Bang, Seung Woo Park, Jae Bock Chung, Si Young Song, Jeong Youp Park   +9 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Second primary cancers in people who had cancer as children: an Australian Childhood Cancer Registry population-based study [PDF]

, 2019
Objective: To investigate the incidence of second primary cancers in people diagnosed with cancer during childhood. Design, setting: Retrospective, population-based study; analysis of Australian Childhood Cancer Registry data.
Baade, Peter D., Baade, Peter D, Moore, Andrew S., Aitken, Joanne F., Moore, Andrew S, Youlden, Danny R., Valery, Patricia C., Valery, Patricia C, Youlden, Danny R, Green, Adèle C., Aitken, Joanne F, Green, Adèle C   +11 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Risk of second primary cancers in women diagnosed with endometrial cancer in German and Swedish cancer registries [PDF]

, 2017
Along with the increasing incidence and favorable prognosis, more women diagnosed with endometrial cancer may develop second primary cancers (SPCs). We aimed at investigating risk of SPCs after endometrial cancer in Germany and Sweden to provide insight ...
Kari Hemminki, Tianhui Chen, Lina Jansen, Jansen, Lina,, Hemminki, Kari, Jansen, Lina, Alexander Katalinic, Fallah, Mahdi,, Luttmann, Sabine, Mahdi Fallah, Bernd Holleczek, Sundquist, Kristina, Hermann Brenner, Ressing, Meike, Fallah, Mahdi, Hemminki, Kari,, Katalinic, Alexander, Karla Geiss, Felipe A. Castro, Geiss, Karla,, Sabine Luttmann, Xu, Leiting, Holleczek, Bernd,, Katalinic, Alexander,, Xu, Leiting,, Brenner, Hermann, Geiss, Karla, Kristina Sundquist, Castro, Felipe A, Castro, Felipe A,, Chen, Tianhui,, Chen, Tianhui, Holleczek, Bernd, Ressing, Meike,, null null, Luttmann, Sabine,, GEKID Cancer Survival Working Group+, Leiting Xu, Brenner, Hermann,, Sundquist, Kristina,, Lund University., Meike Ressing   +41 more
core   +1 more source

Role of chemotherapy for survival in patients with second primary non‐small cell lung cancer

Thoracic Cancer, 2021
Background The therapeutic effect of chemotherapy is still unclear for clinical usage among second primary non‐small cell lung cancer (NSCLC) patients. The aim of this study was to verify the therapeutic effect of chemotherapy and identify the prognostic
Zhile Wang, Yijun Wu, Li Wang, Liang Gong, Chang Han, Fucun Xie, Shanqing Li   +6 more
doaj   +1 more source

Characteristics of second primary breast cancer after ovarian cancer: a Korea central cancer registry retrospective study

Frontiers in Oncology, 2023
BackgroundSecond primary cancer has become an important issue among cancer survivors. This study sought to determine the differences in clinicopathologic outcomes between second primary breast cancer (SPBC) after ovarian cancer and primary breast cancer (
Eun-Gyeong Lee, Jiwon Lim, Hyeong In Ha, Myong Cheol Lim, Myong Cheol Lim, Myong Cheol Lim, Yoon Jung Chang, Yoon Jung Chang, Young-Joo Won, So-Youn Jung, So-Youn Jung   +10 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Family history, genetic testing, and clinical risk prediction: pooled analysis of CHEK2 1100delC in 1,828 bilateral breast cancers and 7,030 controls. [PDF]

, 2009
If breast cancers arise independently in each breast the odds ratio (OR) for bilateral breast cancer for carriers of CHEK2 1100delC should be approximately 5.5, the square of the reported OR for a first primary (OR, 2.34).
Blomqvist, Carl,, Blomqvist, Carl, Peto, Julian, Muhammad U. Rashid, Johnson, Nichola, Fletcher, Olivia, Chekmariova, Elena V., Anna P. Sokolenko, Broeks, Annegien, Kristiina Aittomäki, Christina Justenhoven, Wasielewski, Marijke, Justenhoven, Christina, Alan Ashworth, Heli Nevanlinna, Ute Hamann, Annegien Broeks, Evgeny N. Imyanitov, Schmidt, Marjanka K., Dörk, Thilo, Michael Bremer, Isabel dos Santos Silva, Imyanitov, Evgeny N., Imyanitov, Evgeny N, Carl Blomqvist, Aittomäki, Kristiina, Rashid, Muhammad U., Kilpivaara, Outi, Laura J. Van't Veer, Hiltrud Brauch, Nichola Johnson, van't Veer, Laura J., Outi Kilpivaara, Nevanlinna, Heli, Ashworth, Alan, Hanne Meijers-Heijerboer, Sokolenko, Anna P, Rashid, Muhammad U, Chekmariova, Elena V, Dos Santos Silva, Isabel, Brauch, Hiltrud, Van't Veer, Laura J, Marijke Wasielewski, Sokolenko, Anna P., Thilo Dörk, Olivia Fletcher, Meijers-Heijerboer, Hanne, Schmidt, Marjanka K, Elena V. Chekmariova, Marjanka K. Schmidt, Julian Peto, Bremer, Michael, Hamann, Ute   +52 more
core   +1 more source