Results 71 to 80 of about 14,604,770 (257)

Cancer Trends: Primary Liver Cancer

, 2016
During 2012-2014, a little over half (58%) of all primary liver cancers were histologically confirmed, 37% were diagnosed radiologically only via x-ray, MRI/CT scan etc. and 5% did not have a method of diagnosis specified.
National Cancer Registry Ireland (NCRI)
core  

Abstract PO-150: Epidemiology of endometrial cancer as a second primary malignancy in Florida

, 2020
Background: According to cancer registry data, nearly 20% of Endometrial Cancer (EC) cases in the US are second or higher-order primary cancers. Little is known in regard to the epidemiology of EC as a Second Primary (ECSP) cancer.
Matthew P. Schlumbrecht, Medina, Heidy N., Schlumbrecht, Matthew P., Paulo S. Pinheiro, Heidy N. Medina, Pinheiro, Paulo S.   +5 more
core   +1 more source

Risk of second primary malignancy in breast cancer survivors: A nested population-based case-control study [PDF]

, 2015
Purpose: Evolving therapies have improved the prognoses of patients with breast cancer; and currently, the number of long-term survivors is continuously increasing. However, these patients are at increased risk of developing a second cancer.
FEDERICO, Massimo, SACCHI, Stefano, Cirilli, Claudia, MARCHESELLI, Luigi, FERRI, Paola, Napolitano, Martina, CORTESI, LAURA, MARCHESELLI, Raffaella, BARI, Alessia, POZZI, Samantha   +9 more
core   +1 more source

Does muscle invasive bladder cancer following pelvic radiotherapy portend worse prognosis? A seer-based study

Cancer Treatment and Research Communications, 2020
Background: Although emerging evidence demonstrates increased risk of secondary bladder cancer following pelvic radiotherapy, the aggressiveness of these tumors is not well-characterized. Materials and Methods: A search of the Surveillance, Epidemiology,
Caleb Natale, Gabriel Leinwand, Farid Zeineddine, Jonathan L Silberstein, Louis S Krane   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Increased prevalence of colorectal adenomas in women with breast cancer [PDF]

, 2005
Background: The frequency of colorectal adenomas and carcinomas was investigated in a large cohort of women with breast cancer in comparison with matched controls, since data on the occurrence of second tumors in women with breast cancer is controversial.
Späth, Lydia, Eiermann, Wolfgang, Sackmann, Michael, Göke, Burkhard, Ochsenkühn, Thomas, Wiebecke, Baldur, Bayerdörffer, Ekkehard, Meining, Alexander, Mannes, Gerd Alexander, Ochsenkühn, T;Bayerdörffer, E;Meining, A;Späth, L;Mannes, GA;Wiebecke, B;Eiermann, W;Sackmann, M;Göke, B   +9 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Cancer Trends: Breast cancer 1994-2016

, 2019
There were 62,052 cases of newly diagnosed invasive or in situ breast tumours registered in Ireland by the National Cancer Registry for the period 1994–2016, of which 56,366 were invasive (ICD10: C50) and 5,686 were carcinoma in situ (ICD10: D05 ...
National Cancer Registry Ireland (NCRI)
core  

Breast cancer following ovarian cancer: Public health and screening implications for the leading female malignancy through Meta-analysis

Clinical Epidemiology and Global Health
Objective: To evaluate the incidence of breast cancer after a diagnosis of ovarian cancer, considering key factors such as BRCA mutation status and age at ovarian cancer diagnosis.
Nada Bennani Mechita, Samia El Hilali, Anas Ahmed Mountassir, Sara Messaoud, Rachid Razine, Majdouline Obtel   +5 more
doaj   +1 more source