Results 41 to 50 of about 452,511 (266)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Омский научный вестник: Серия "Авиационно-ракетное и энергетическое машиностроение"The article examines the effectiveness of the absorption bromistolithium refrigerating machine in an air conditioning system at a synthetic resin production facility using waste steam.
O. S. Malinina, I. A. Zaitsev
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Energies, 2016 With the proportion of air conditioners increasing gradually, they can provide a certain amount of frequency-controlled reserves for a micro-grid. Optimizing utilization of air conditioners and considering load response characteristics and customer ...
Qingzhu Wan, Yuan Bian, Yalan Chen
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Analysis and Simulation of Forced Ventilation in Special Condition
MATEC Web of Conferences, 2018 The research subject of the current work is heating of the closed area by the forced air ventilation system with heat recovery ventilator and floor radiators. The simulation model was made in ANSYS Fluent 14.0. In the simulation were taken to account the
Rimár Miroslav +3 more
doaj +1 more source
On the Complexity and the Handling of Multi-X Simulations in the Secondary Air System [PDF]
The secondary air system (SAS) has paramount impact on the safe operation, remaining service life and overall efficiency of aero engines. Due to the manifold interactions with other engine components, there is demand for effective consideration of the SAS in various processes along the engine life cycle. 1D fluid network models are the state of the art
Woelki, Dominik +3 more
openaire +1 more source