Results 51 to 60 of about 1,718,290 (313)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Research on a Micro-Grid Frequency Modulation Strategy Based on Optimal Utilization of Air Conditioners

Energies, 2016
With the proportion of air conditioners increasing gradually, they can provide a certain amount of frequency-controlled reserves for a micro-grid. Optimizing utilization of air conditioners and considering load response characteristics and customer ...
Qingzhu Wan, Yuan Bian, Yalan Chen
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Vrishabhavathi Valley Wastewater Treatment Plant System Upgrade [PDF]

, 2017
Sixteen activated sludge tanks, eight secondary clarifiers, and four return pump stations were designed for the Vrishabhavathi Wastewater Treatment plant in Bangalore India.
Chellaram, Vijay, Miller, Christian
core   +1 more source

Biological implications of high-energy cosmic ray induced muon flux in the extragalactic shock model

, 2011
A ~ 62 My periodicity in fossil biodiversity has been observed in independent studies of paleontology databases over ~0.5Gy. The period and phase of this biodiversity cycle coincides with the oscillation of our solar system normal to the galactic disk ...
Adrian L. Melott, Alpen, Arens, Atri, Atri, Bailer-Jones, Chen, Cornette, Cucinotta, Dimitra Atri, Ferrari, Feulner, Gies, Groom, Hebbeker, Karam, Kirkby, Lieberman, McNulty, Medvedev, Melott, Melott, Melott, Melott, Melott, O'Brien, Pelliccioni, Rohde, Simonsen, Usoskin   +29 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Analysis and Simulation of Forced Ventilation in Special Condition

MATEC Web of Conferences, 2018
The research subject of the current work is heating of the closed area by the forced air ventilation system with heat recovery ventilator and floor radiators. The simulation model was made in ANSYS Fluent 14.0. In the simulation were taken to account the
Rimár Miroslav, Kulikov Andrii, Fedak Marcel, Abraham Milan   +3 more
doaj   +1 more source

Dispatch for Urban Integrated Heat and Power System Considering Secondary PM2.5 Under Smart Environmental Sensing

IEEE Access, 2019
To improve the air quality and reduce the human settlement pollution, the effects of initial air pollutant emissions from urban heat and power generation with the diffusion of pollutants were often considered in the energy system dispatch, but the ...
Sicheng Peng, Hongxia Wang, Yuqiong Zhang, Dichen Liu, Jinchang Li, Hengrui Ma   +5 more
doaj   +1 more source

Gas-turbine engine secondary air system analysis

Izvestiya MGTU MAMI, 2015
Secondary air system model based on graph theory and one dimentional hydraulic models is discussed. Channel inclination to major axis of integration is taking into account. New hydraulic channel model for smooth transition between “horizontal” and “vertical” flow passages is proposed.
openaire   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source