Results 51 to 60 of about 273,928 (312)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Development of a measuring system for determining the air density correction factor for ionization chambers open to the atmosphere [PDF]
Nuclear Technology and Radiation ProtectionThis paper introduces a measuring system designed to determine the air density correction factor for ionization chambers open to the atmosphere. The system is intended for use in clinical and radiotherapy facilities, secondary standard dosimetry
Đaletić Miloš V.
doaj +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Studies on SI engine simulation and air/fuel ratio control systems design [PDF]
, 2013 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.More stringent Euro 6 and LEV III emission standards will immediately begin execution on 2014 and 2015 respectively.
Bai, Yang, Yang Bai
core
IEEE Access, 2019 To improve the air quality and reduce the human settlement pollution, the effects of initial air pollutant emissions from urban heat and power generation with the diffusion of pollutants were often considered in the energy system dispatch, but the ...
Sicheng Peng +5 more
doaj +1 more source
Impact of low-pressure systems on winter heavy air pollution in the northwest Sichuan Basin, China [PDF]
Atmospheric Chemistry and Physics, 2018 The cities of Chengdu, Deyang, and Mianyang in the northwest Sichuan Basin are part of a rapidly developing urban agglomeration adjoining the eastern slopes of the Tibetan Plateau.
G. Ning +11 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Journal of Telecommunications and Information Technology, 2021 The article describes interference affecting the operation of radiolocation and radionavigation devices used in the air traffic surveillance systems, caused by the proximity of building structures. The impact of a hypothetical structure on the operation
Maciej J. Grzybkowski +2 more
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source