Results 61 to 70 of about 273,990 (313)

Implicit Heterogeneous 1D/2D Coupling for Aero-Thermo-Mechanical Simulation of Secondary Air Systems [PDF]

, 2015
The paper presents a computational procedure for heterogeneous coupled analysis of 1D flow network models of air engine secondary air systems and 2D/3D solid thermo-mechanical finite element models of engine components. We solve an unsteady heat transfer
Turner, Lynne, Ganine, Vlad, Curzons, Steve, Hills, Nick, Miller, MC, Peter Smout, Nick Hills, Steve Curzons, Barnes, CJ, Chris Barnes, Lynne Turner, Matt Miller, GANINE, VLADISLAV, Vlad Ganine, Smout, PD   +14 more
core   +1 more source

Impact of Structures on the Operation of Air Traffic Radiolocation and Radionavigation Surveillance Systems

Journal of Telecommunications and Information Technology, 2021
The article describes interference affecting the operation of radiolocation and radionavigation devices used in the air traffic surveillance systems, caused by the proximity of building structures. The impact of a hypothetical structure on the operation
Maciej J. Grzybkowski, Daniel Niewiadomski, Marcin Mora   +2 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Cost-optimization model to design and operate hybrid heating systems – Case study of district heating system with decentralized heat pumps in Finland [PDF]

, 2023
Funding Information: Decentralized electrification means utilizing small- and medium scale electricity-driven heat production technologies in secondary side of district heating network, i.e. in buildings. These can be e.g.
Pesola, Aki, Aki Pesola
core   +1 more source

Enhancing the detection capability of secondary radar for dense targets

Dianzi Jishu Yingyong
Secondary radar systems primarily detect cooperative targets through an interrogation-response mechanism and are extensively applied in fields such as air traffic control.
Yang Jie, Lai Jiaqing
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Spatial homogeneity of air in a mushroom tunnel: Single vs. boost duct air distribution systems [PDF]

, 2001
Air can become stratified in a standard mushroom tunnel using a single-duct air distribution system. Stratification can be overcome by increased air circulation, such as the addition of a secondary air distribution duct, i.e., a boost duct air ...
Ringwood, John, Martin, David, Grant, James J.   +2 more
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source