Results 51 to 60 of about 4,197,741 (336)

Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling. [PDF]

, 2015
Alkyl oxalates are new bench-stable alcohol-activating groups for radical generation under visible light photoredox conditions. Using these precursors, the first net redox-neutral coupling of tertiary and secondary alcohols with electron-deficient ...
Jamison, Christopher R, MacMillan, David WC, Nawrat, Christopher C, Overman, Larry E, Slutskyy, Yuriy   +4 more
core  

Sugar Alcohols Have a Key Role in Pathogenesis of Chronic Liver Disease and Hepatocellular Carcinoma in Whole Blood and Liver Tissues. [PDF]

, 2020
The major risk factors for hepatocellular carcinoma (HCC) are hepatitis C and B viral infections that proceed to Chronic Liver Disease (CLD). Yet, the early diagnosis and treatment of HCC are challenging because the pathogenesis of HCC is not fully ...
El-Said, Hala, Elfert, Ashraf, Fiehn, Oliver, Helal, Marwa, Ismail, Israa T, Salama, Ibrahim   +5 more
core   +2 more sources

Cp*Co(iii)-catalyzed N-alkylation of amines with secondary alcohols

Organic Chemistry Frontiers, 2019
We report here the first high-valent cobalt(iii)-catalyzed direct alkylation of aromatic amines with secondary alcohols.
Balakumar Emayavaramban, P. Chakraborty, E. Manoury, R. Poli, Basker Sundararaju   +4 more
semanticscholar   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Syntheses of Enantiopure Aliphatic Secondary Alcohols and Acetates by Bioresolution with Lipase B from <em>Candida antarctica</em>

Molecules, 2012
The lipase B from <em>Candida antarctica</em> (Novozym 435^®, CALB) efficiently catalyzed the kinetic resolution of some aliphatic secondary alcohols: (±)-4-methylpentan-2-ol (<strong>1</strong>), (±)-5 ...
Richele P. Severino, Hercules V. Ferreira, André L. M. Porto, Lenilson C. Rocha   +3 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Effects of small amounts of pentadecan-2-one on the growth of Clostridium butyricum.

Journal of Lipid Research, 1978
Primary alcohols occur as trace lipids and are the only long-chain alcohol species present in Clostridium butyricum. Secondary alcohols do not occur physiologically in this microorganism.
J R Gilbertson, R A Gelman, T H Chiu, L I Gilbertson, T E Knauer   +4 more
doaj   +1 more source

Interstitial nitrogen-induced efficiency alcohol oxidation over heterogeneous N–CoMn2O4 catalyst under visible-light

Green Synthesis and Catalysis, 2023
Developing highly efficient and recyclable photocatalysts through harvesting solar light as energy is crucial to oxidation for industrial implementation, especially for simple transition metal oxidic catalysts without precious/heavy/rare metal dopants ...
Hongwei Li, Yurong Zhang, Jun Tang, Guozheng Huang, Ping Cui, Qingping Ke   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Electrochemical oxidation of sec-alcohols with MgBr2·6H2O

Tetrahedron Green Chem, 2023
The electrochemical oxidation of sec-alcohols has been achieved using MgBr2·6H2O as an inexpensive active bromine source and electrolyte under constant current conditions.
Kosuke Yamamoto, Takumi Inoue, Natsumi Hanazawa, Masami Kuriyama, Osamu Onomura   +4 more
doaj   +1 more source