Results 31 to 40 of about 58,921 (259)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

A comparative LFER study of the reactivity of pyridineacetic, pyridineacetic acids N-oxide and substituted phenylacetic acids with diazodiphenylmethane in various alcohols [PDF]

open access: yesJournal of the Serbian Chemical Society, 2000
Rate constants have been determined for the reactions of diazodiphenylmethane (DDM) with 3- and 4-pyridineacetic acid, 3- and 4-pyridineacetic acid N-oxide and some meta- and para-substituted phenylacetic acids in twelve alcohols. The determined
Drmanić Saša Z.   +2 more
doaj   +3 more sources

OXIDATION OF BENZYLIC SECONDARY ALCOHOL WITH PYRIDINIUM CHLOROCHROMATE-ALUMINA (PCC-Al2O3)

open access: yesIndonesian Journal of Chemistry, 2010
In these studies, Pyridinium chlorochromate-Alumina was used for oxidation of secondary alcohols (safryl alcohol and methyleugenyl alcohol) to ketone.  The oxidation of safryl alcohol with PCC-Al2O3 followed by purification by potassium bisulfite yields ...
Hanoch J. Sohilait
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Effects of small amounts of pentadecan-2-one on the growth of Clostridium butyricum.

open access: yesJournal of Lipid Research, 1978
Primary alcohols occur as trace lipids and are the only long-chain alcohol species present in Clostridium butyricum. Secondary alcohols do not occur physiologically in this microorganism.
J R Gilbertson   +4 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Syntheses of Enantiopure Aliphatic Secondary Alcohols and Acetates by Bioresolution with Lipase B from <em>Candida antarctica</em>

open access: yesMolecules, 2012
The lipase B from <em>Candida antarctica</em> (Novozym 435<sup>®</sup>, CALB) efficiently catalyzed the kinetic resolution of some aliphatic secondary alcohols: (±)-4-methylpentan-2-ol (<strong>1</strong>), (±)-5 ...
Richele P. Severino   +3 more
doaj   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han   +8 more
wiley   +1 more source

A Study of Amino Acid Metabolism and the Production of Higher Alcohols and Their Esters in Sparkling Wines

open access: yesFermentation
The presented article is focused on the study of amino acid metabolism and the related production of fusel alcohols and their esters in the secondary fermentation of sparkling wines.
Štěpán Tesařík   +3 more
doaj   +1 more source

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