Results 61 to 70 of about 7,970,747 (301)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

The Shared Fate of Two Innovations in Qualitative Methodology: The Relationship of Qualitative Software and Secondary Analysis of Archived Qualitative Data

open access: yesForum: Qualitative Social Research, 2000
This article considers the contribution that software to support qualitative data analysis can make in the secondary analysis of qualitative data. The article suggests some benefits of secondary analysis of qualitative data and addresses some of the ...
Nigel Fielding
doaj  

The placebo effect revisited

open access: yesScandinavian Journal of Work, Environment & Health, 2012
Andersen et al (1) recently published data from a study on brief daily exercise and headache. They reported that a 10-week intervention with 2 minutes of daily exercise using an elastic tube caused a decrease in headache frequency from 1.4 to 0.9 days ...
Johan H Andersen, Sigurd Mikkelsen
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Secondary Analysis of Qualitative Interview Data: Objections and Experiences. Results of a German Feasibility Study

open access: yesForum: Qualitative Social Research, 2011
The German feasibility study on archiving and reusing qualitative interview data has surveyed experts, namely qualitative researchers. Their views, ideas and problems have to be considered as central conditions if the aim is to open up the horizon for ...
Irena Medjedović
doaj  

The placebo effect revisited – author response

open access: yesScandinavian Journal of Work, Environment & Health, 2012
Our randomized controlled trial showed a reduction of neck/shoulder pain and headache in response to 10 weeks of resistance training performed for 2 minutes a day (1, 2).
Lars L Andersen
doaj   +1 more source

An analysis of PGCE models: Key stakeholder perceptions from the secondary phase [PDF]

open access: yes, 2013
The aim of this research was to explore the two most popular PGCE models now in operation, for which there is little research to-date, from the perspectives of key stakeholders from the secondary phase in two higher education institutions (HEIs) in ...
Thomas, Lorraine
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Potentials and Limits of Secondary Analysis in a Specific Applied Context: The Case of EDF—Verbatim

open access: yesForum: Qualitative Social Research, 2005
In this paper we present the results of secondary analyses conducted on documents recorded in VERBATIM, the qualitative data archiving system and database developed by the Sociological Surveys Department (GRETS) of Electricité de France (EDF).
Magdalini Dargentas, Dominique Le Roux
doaj  

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