Results 181 to 190 of about 323,138 (302)

Efficacy and safety of the long-term oral administration of carprofen in the treatment of osteoarthritis in dogs [PDF]

open access: yes, 2007
The aim of this study conducted in France was to confirm the efficacy and safety of the oral administration of carprofen (Rimadyl®) at 4 mg/kg once a day during four months in the treatment of clinically chronic osteoarthritis in dogs.
Autefage, André, Gosselin, Jacques
core  

Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding   +10 more
wiley   +1 more source

Emerging role of the crosstalk between gut microbiota and liver metabolome of subterranean herbivores in response to toxic plants

open access: yesEcotoxicology and Environmental Safety
Plant secondary metabolites (PSMs) are a defense mechanism against herbivores, which in turn use detoxification metabolism to process ingested and absorbed PSMs.
Yuchen Tan   +5 more
doaj   +1 more source

Radium Speciation in Simulated Digestive Biofluids: Insights from Electrospray Ionization Mass Spectrometry and Thermodynamic Modeling

open access: yesAnalysis &Sensing, EarlyView.
Electrospray ionization mass spectrometry (ESI‐MS) combined with thermodynamic modeling provides the first direct characterization of radium speciation in synthetic gastrointestinal biofluids. Free Ra2+ ions predominate with minimal protein binding and negligible EDTA complexation. Crown ethers enable effective Ra complexation.
Linus Holtmann   +5 more
wiley   +1 more source

Dietary Baicalin Supplementation Can Enhance the Growth Performance of Weaned Piglets and Maintain the Intestinal Barrier Integrity

open access: yesAnimal Research and One Health, EarlyView.
This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao   +6 more
wiley   +1 more source

Su1880 – Secondary Bile Acids Protect Against Intestinal Inflammation Via Bile Acid Tgr5 Receptor

open access: yesGastroenterology, 2019
Sidhartha R. Sinha   +8 more
openaire   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

open access: yesAnimal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou   +4 more
wiley   +1 more source

Parabacteroides distasonis Alleviates Obesity and Metabolic Dysfunctions via Production of Succinate and Secondary Bile Acids.

open access: yesCell Reports, 2019
Kai Wang   +11 more
semanticscholar   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

open access: yesAnimal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke   +9 more
wiley   +1 more source

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