Using a Project-Based Blended Learning Program to Enhance EFL Secondary Stage Al-Azhar Students' Psychological Flow [PDF]
Wafaa Ahmed Mahmoud Mohammed
openalex +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Optimization on Secondary Flow and Auxiliary Entrainment Inlets of an Ejector by Using Three-Dimensional Numerical Study. [PDF]
Yan J, Jiang J, Wang Z.
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Secondary Flow Effect on Supercritical Kerosene Oxidation Deposition and Heat Transfer in a Coiled Tube. [PDF]
Pei X, Tian H, Zheng Z, Wang Y, Hou L.
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Numerical simulation of flows in curved diffusers with cross-sectional transitioning using a three-dimensional viscous analysis [PDF]
A three dimensional analysis for fully viscous, subsonic, compressible flow is evaluated. An approximate form of the Navier Stokes equations is solved by an implicit spatial marching technique.
Anderson, B. H., Towne, C. E.
core +1 more source
We present 3D hydrodynamical simulations of a jet launched from the secondary star of a binary system inside a proto-planetary nebula. The secondary star moves around the primary in a close eccentric orbit.
Alejandro C. Raga +29 more
core +1 more source

