Results 101 to 110 of about 3,135,634 (302)
Influence of blade geometry on secondary flow development in a transonic centrifugal compressor
Journal of the Global Power and Propulsion Society, 2018 Due to the increasing demand for higher efficiencies of centrifugal compressors, numerical optimization methods are becoming more and more relevant in the design process.
Moritz Mosdzien +4 more
doaj +1 more source
Numerical simulation of flows in curved diffusers with cross-sectional transitioning using a three-dimensional viscous analysis [PDF]
A three dimensional analysis for fully viscous, subsonic, compressible flow is evaluated. An approximate form of the Navier Stokes equations is solved by an implicit spatial marching technique.
Anderson, B. H., Towne, C. E.
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Journal of Thermal Science and Technology, 2017 A parametric investigation of secondary flow control using endwall vortex generator jet (VGJ) is performed in a high turning compressor cascade. The mechanisms for the variations of VGJ performance with different jet parameters including the pitch angle,
Huaping LIU +4 more
doaj +1 more source
Comparison of visualized turbine endwall secondary flows and measured heat transfer patterns [PDF]
Various flow visualization techniques were used to define the secondary flows near the endwall in a large heat transfer data. A comparison of the visualized flow patterns and the measured Stanton number distribution was made for cases where the inlet ...
Gaugler, R. E., Russell, L. M.
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Reducing Secondary Flow Losses in Low-Pressure Turbines: The “Snaked” Blade
International Journal of Turbomachinery, Propulsion and Power, 2019 This paper presents an innovative design for reducing the impact of secondary flows on the aerodynamics of low-pressure turbine (LPT) stages. Starting from a state-of-the-art LPT stage, a local reshaping of the stator blade was introduced in the end-wall
Matteo Giovannini +4 more
doaj +1 more source
Derivation and evaluation of an approximate analysis for three-dimensional viscous subsonic flow with large secondary velocities [PDF]
An approximate analysis is presented for calculating three-dimensional, low Mach number, laminar viscous flows in curved passages with large secondary flows and corner boundary layers.
Anderson, O. L. +2 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source