Results 81 to 90 of about 3,130,306 (355)

Turbulent boundary layers with secondary flow [PDF]

open access: yes
An experimental analysis of the boundary layer on a plane wall, along which the flow occurs, whose potential flow lines are curved in plane parallel to the wall is discussed. According to the equation frequently applied to boundary layers in a plane flow,
Grushwitz, E.
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Operation in the turbulent jet field of a linear array of rectangular jets using a normal two-dimensional jet (Variation of mean velocity field)

open access: yesNihon Kikai Gakkai ronbunshu, 2014
The mean flowfield of a linear array of multiple rectangular jets run through transversely with a normal two-dimensional jet, has been investigated, experimentally. The purpose of this experiment is to operate both the velocity scale and the length scale
Shigetaka FUJITA, Takashi HARIMA
doaj   +1 more source

Further development of a method for computing three-dimensional subsonic viscous flows in turbofan lobe mixers [PDF]

open access: yes
Procedure for computing subsonic, turbulent flow in turbofan lobe mixers was extended to allow consideration of flow fields in which a swirl component of velocity may be present.
Briley, W. R.   +3 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

NUMERICAL SIMULATION AND THEORETICAL ANALYSIS OF THE 3D VISCOUS FLOW IN CENTRIFUGAL IMPELLERS

open access: yesTASK Quarterly, 2001
This paper investigates the three-dimensional viscous flow in centrifugal impellers through theoretical analysis and numerical simulations, which is a summary of the authors’ recent work.
SHUN KANG, CHARLES HIRSCH
doaj  

Semi‐Analytical Models for Predicting the Maximum Longitudinal Flow Velocity in the Confluence Channel

open access: yesWater Resources Research
In a channel confluence, different hydrodynamic characteristics can significantly affect the flow structure. As the main and tributary flow converges at the confluence, they are constrained by the recirculation zone, resulting in streamline contraction ...
Haokun Feng   +5 more
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Evolution of secondary cellular circulation flow above submarine bedforms imaged by remote sensing techniques [PDF]

open access: yes, 2013
Normalized radar cross section (NRCS) modulation and acoustic Doppler current profiler (ADCP) measurements above submarine sand ribbons and sand waves are presented. The two study areas are located in the Southern Bight of the North Sea at the Birkenfels
Hennings, Ingo, Herbers, Dagmar
core  

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