Results 111 to 120 of about 7,891,124 (254)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Research on Optimal Allocation Method of Secondary Frequency Modulation Capacity of Battery Energy Storage Based on Antlion Algorithm

open access: yesTaiyuan Ligong Daxue xuebao
[Purposes] At present, the high proportion of new energy connected to the power system leads to severe challenges to its frequency stability and power quality.
XIAO Chun
doaj   +1 more source

Raising public awareness and trust in transmission infrastructure projects with incentive regulation : tools and biases [PDF]

open access: yes, 2018
Raising public awareness and trust in transmission infrastructure development is one of the key current challenges facing Transmission System Operators (TSOs) and other project developers. The result can be costly delays.
KEYAERTS, Nico   +2 more
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Capacity allocation method for a hybrid energy storage system participating in secondary frequency regulation based on variational mode decomposition

open access: yesInternational Journal of Electrical Power & Energy Systems
Hybrid Energy Storage Systems (HESSs) are extensively employed to address issues related to frequency fluctuations. This paper introduces a method for configuring the capacity of a HESS engaged in the secondary frequency regulation, utilizing Variable ...
Taiying Zheng, Minghao Ye, Qinghua Wu
doaj   +1 more source

On robust load frequency regulation in a new multi-machine power system structure [PDF]

open access: yes, 2003
The siting of numerous generator units in distribution\ud areas is being encouraged by the current deregulation of the\ud industry is likely to have an impact on the frequency\ud regulation of the existing power systems, which designed to\ud operate with
Mitani, Yasunori   +2 more
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Discretionary Investing by ‘Passive’ S&P 500 Funds

open access: yes
This page contains the code and data necessary to replicate the results of "Discretionary Investing by ‘Passive’ S&P 500 Funds" by Peter Molk & Adriana Z. Robertson, published in the Yale Journal on Regulation (2024)
Journal on Regulation, Yale
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

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