Results 41 to 50 of about 358,306 (251)

Time to Diagnosis Among Children and Adolescents With Cancer in Québec, Canada: A Population‐Based Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen   +5 more
wiley   +1 more source

Unified centralised/decentralised frequency control structure for microgrids

open access: yesIET Renewable Power Generation, 2021
When the microgrid (MG) operates in islanded mode, the frequency adjustment is performed through the secondary control. This control can be achieved through centralised, distributed or decentralised strategies.
Paulo Thiago deGodoy   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A data-driven modeling method for secondary frequency regulation characteristic of thermal power units

open access: yesZhejiang dianli
The existing mechanism models for thermal power units face challenges in accurately reflecting unit response characteristics and obtaining precise model parameters.
LI Zhijun   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Strategy of Wind-Storage Combined System Participating in Power System Secondary Frequency Regulation Based on Model Predictive Control

open access: yesShanghai Jiaotong Daxue xuebao
With the increasing penetration of wind power in power grids, it is necessary for wind storage joint farms to participate in power grid frequency modulation to maintain frequency stability of the power grid. By analyzing the mechanical characteristics of
LIU Chuanbin, JIAO Wenshu, WU Qiuwei, CHEN Jian, ZHOU Qian
doaj   +1 more source

Coordinated Secondary Frequency Regulation Strategy of Doubly-Fed Induction Generator and Electric Vehicle

open access: yesApplied Sciences, 2019
Wind turbines can participate in frequency regulation by controlling active power output, but the indeterminacy and volatility of wind power result in low reliability of frequency support.
Qian Zhang   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Frequency regulation optimization for thermal-wind-storage systems considering unit characteristics and energy storage state of charge recovery

open access: yes电力工程技术
With the continuous rise of renewable energy penetration in China's power system, thermal-wind-storage systems need to carry out joint frequency regulation response according to their unit characteristics. To improve the automatic generation control (AGC)
Shenyou WANG, Pengfei HU, Shaojia DANG
doaj   +1 more source

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