Results 51 to 60 of about 7,891,124 (254)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

A data-driven modeling method for secondary frequency regulation characteristic of thermal power units

Zhejiang dianli
The existing mechanism models for thermal power units face challenges in accurately reflecting unit response characteristics and obtaining precise model parameters.
LI Zhijun, SHA Qianli, YAN Xinrong, YAN Gangui, ZHU Lin, FANG Zheng, LI Junhui   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Internal ribosomal entry site lacks secondary structure [PDF]

, 2007
The search for mechanisms of translational regulation has yielded many experimentally identified internal ribosome entry sites (IRES). Because of the lack of sequence similarity among the experimentally IRESs, it is widely assumed that IRESs posses ...
Xuhua Xia
core  

Replication Data for: Privacy for Sale: The Law of Transactions in Consumers’ Private Data

, 2023
This page contains the code and instructions necessary to replicate the results of "Privacy for Sale: The Law of Transactions in Consumers’ Private Data" by Christopher G. Bradley, published in the Yale Journal on Regulation (2023)
Yale Journal on Regulation
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Strategy of Wind-Storage Combined System Participating in Power System Secondary Frequency Regulation Based on Model Predictive Control

Shanghai Jiaotong Daxue xuebao
With the increasing penetration of wind power in power grids, it is necessary for wind storage joint farms to participate in power grid frequency modulation to maintain frequency stability of the power grid. By analyzing the mechanical characteristics of
LIU Chuanbin, JIAO Wenshu, WU Qiuwei, CHEN Jian, ZHOU Qian
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Unified centralised/decentralised frequency control structure for microgrids

IET Renewable Power Generation, 2021
When the microgrid (MG) operates in islanded mode, the frequency adjustment is performed through the secondary control. This control can be achieved through centralised, distributed or decentralised strategies.
Paulo Thiago deGodoy, Adriano Batista deAlmeida, Diogo Marujo   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source