Results 51 to 60 of about 358,306 (251)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Self-Adaptive Secondary Frequency Regulation Strategy Based on Distributed Model Predictive Control

open access: yesShanghai Jiaotong Daxue xuebao
To address the issues of reduced adaptability of secondary frequency regulation caused by changes in power system parameters, a self-adaptive secondary frequency regulation strategy based on distributed model predictive control (DMPC) is proposed. First,
CAO Yongji, ZHANG Jiangfeng, WANG Tianyu, ZHENG Keke, WU Qiuwei
doaj   +1 more source

Wind farms providing secondary frequency regulation: evaluating the performance of model-based receding horizon control [PDF]

open access: yesWind Energy Science, 2018
This paper is an extended version of our paper presented at the 2016 TORQUE conference (Shapiro et al., 2016). We investigate the use of wind farms to provide secondary frequency regulation for a power grid using a model-based receding horizon control ...
C. R. Shapiro   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Inter-Provincial Tie-Line Power Assessment Mechanism and Model for Spot Market

open access: yesShanghai Jiaotong Daxue xuebao
Multiple regional power grids in China have adopted the control performance standard (CPS) to assess the performance of inter-provincial tie-line operations, which has played a significant role in the reduction of both power deviation on inter-provincial
CHEN Zijie, SONG Bingbing, LI Yutong, WANG Lifeng, TENG Xiaobi, YAN Zheng, CHEN Sijie
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Coordinated Bidding and Distributed Tracking Control for Secondary Frequency Regulation in Multi-Site Charging Networks with Charging Service Safeguards

open access: yesEnergies
The rapid integration of renewable energy is increasing the need for fast and sustained load-side frequency regulation, and public electric vehicle (EV) charging networks are promising providers.
Bo Peng   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Multi-Source Coordinated Control and Parameter Optimization Methods for Frequency Stability in High-Proportion New Energy Sending-End Systems [PDF]

open access: yesDianli jianshe
[Objective] Constructing renewable energy transmission systems is a key approach for addressing the uneven spatial distribution of resources. However, integrating a high proportion of renewable energy poses significant challenges to the frequency ...
JIANG Minghua, LI Ding, KONG Dezhen, WANG Zhuxiu, BAI Ningning, LI Zhongwen
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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