Results 51 to 60 of about 358,984 (291)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Virtual Synchronous Generator Control Strategy Based on Shipborne Three-Phase Two-Level DC–AC Converters

open access: yesJournal of Marine Science and Engineering
In response to the International Maritime Organization’s emission reduction targets, ship power systems are transitioning toward microgrid architectures with high renewable energy penetration.
Gufeng Jiang   +3 more
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Frequency Regulation by Management of Building Cooling Systems through Model Predictive Control [PDF]

open access: yes, 2014
Frequency stability in power systems is a key driver for the maintenance of supply quality. Thermal loads, if properly managed, can play an important role in providing support to the frequency regulation.
S. Massucco   +5 more
core   +1 more source

Unified centralised/decentralised frequency control structure for microgrids

open access: yesIET Renewable Power Generation, 2021
When the microgrid (MG) operates in islanded mode, the frequency adjustment is performed through the secondary control. This control can be achieved through centralised, distributed or decentralised strategies.
Paulo Thiago deGodoy   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

A data-driven modeling method for secondary frequency regulation characteristic of thermal power units

open access: yesZhejiang dianli
The existing mechanism models for thermal power units face challenges in accurately reflecting unit response characteristics and obtaining precise model parameters.
LI Zhijun   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Strategy of Wind-Storage Combined System Participating in Power System Secondary Frequency Regulation Based on Model Predictive Control

open access: yesShanghai Jiaotong Daxue xuebao
With the increasing penetration of wind power in power grids, it is necessary for wind storage joint farms to participate in power grid frequency modulation to maintain frequency stability of the power grid. By analyzing the mechanical characteristics of
LIU Chuanbin, JIAO Wenshu, WU Qiuwei, CHEN Jian, ZHOU Qian
doaj   +1 more source

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