Results 61 to 70 of about 358,306 (251)
EnergiesHigh wind power penetration aggravates power system inertia scarcity, and wind turbines switching to MPPT mode after virtual inertia support induces secondary frequency drop (SFD), impairing grid frequency stability.
Guodong Song +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Multi-Timescale Modeling Framework of Hybrid Power Plants Providing Secondary Frequency Regulation
IEEE Open Access Journal of Power and EnergyHybrid power plants (HPPs) present a promising solution to address the significant challenges posed by the rapid integration of variable renewable energy sources (VREs) into power systems, particularly in maintaining power balance and frequency stability.
Yuxin Deng +3 more
doaj +1 more source
Active Frequency Support Control Strategy for Wind Farm Considering the Energy Discrepancy of Wind Turbines [PDF]
Dianli jianshe[Objective] Wind turbine generators generally operate in maximum power point tracking （MPPT） mode and do not provide inertial response and frequency support to the power grid.
LI Fengneng, YANG Ping, WEI Zhichu, CHEN Wenhao, ZHOU Qianyufan, WAN Siyang
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Regulating Secondary Markets in the High Frequency Age: A Principled and Coordinated Approach
Michigan Business & Entrepreneurial Law Review, 2016 Technological developments in securities markets, most notably high frequency trading, have fundamentally changed the structure and nature of trading over the past 50 years. Policymakers both domestically and abroad now face many new challenges impacting the secondary market’s effectiveness as a generator of economic growth and stability.
openaire +2 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
EnergiesWith the increasing proportion of renewable energy in power grids, the inertia level and frequency regulation capability of modern power systems have declined. In response, this paper proposes a coordinated frequency regulation strategy integrating power
Yangqing Dan +6 more
doaj +1 more source