Results 81 to 90 of about 358,984 (291)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Simultaneous economic dispatch and frequency regulation of power systems [PDF]

open access: yes, 2019
Various examples are provided for feedback control of power systems. The feedback control can provide simultaneous frequency regulation and economic operation of a power system.
Fan, Lingling, Miao, Zhixin
core   +1 more source

Coordinated Frequency Regulation between DFIG-VSWTs and BESS Hybrid Systems [PDF]

open access: yes
As the utilization of wind power systems continues to increase, reducing overall system inertia, there is a consequential negative impact on the power system’s ability to regulate frequency.
Manh-Hai Pham   +2 more
core   +1 more source

Multi-Timescale Modeling Framework of Hybrid Power Plants Providing Secondary Frequency Regulation

open access: yesIEEE Open Access Journal of Power and Energy
Hybrid power plants (HPPs) present a promising solution to address the significant challenges posed by the rapid integration of variable renewable energy sources (VREs) into power systems, particularly in maintaining power balance and frequency stability.
Yuxin Deng   +3 more
doaj   +1 more source

Active Frequency Support Control Strategy for Wind Farm Considering the Energy Discrepancy of Wind Turbines [PDF]

open access: yesDianli jianshe
[Objective] Wind turbine generators generally operate in maximum power point tracking (MPPT) mode and do not provide inertial response and frequency support to the power grid.
LI Fengneng, YANG Ping, WEI Zhichu, CHEN Wenhao, ZHOU Qianyufan, WAN Siyang
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Demonstration of heating, ventilation and air conditioning chiller control for power grid frequency regulation [PDF]

open access: yes, 2015
Thesis: S.M. in Building Technology, Massachusetts Institute of Technology, Department of Architecture, 2015.Cataloged from student-submitted PDF version of thesis.Includes bibliographical references (pages 74-77).Secondary frequency regulation is a ...
Su, Po-An (Po-An Leo)
core  

A maximum power loading factor (MPLF) control strategy for distributed secondary frequency regulation of islanded microgrid [PDF]

open access: yes, 2018
Microgrids rely on both primary and secondary frequency control techniques to maintain system stability. Secondary frequency control effectively minimizes frequency fluctuations by adjusting the active power reference in each power inverter, but requires
Zhang, Xin   +5 more
core   +1 more source

A Coordinated Frequency Regulation Strategy Integrating Power Generation, Energy Storage, and DC Transmission for Offshore Wind Power MMC-HVDC Transmission Systems

open access: yesEnergies
With the increasing proportion of renewable energy in power grids, the inertia level and frequency regulation capability of modern power systems have declined. In response, this paper proposes a coordinated frequency regulation strategy integrating power
Yangqing Dan   +6 more
doaj   +1 more source

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