Results 91 to 100 of about 3,074,415 (252)

Isolation, Cultivation AND Differentiation of bulge hair follicle stem cells [PDF]

Background & Aims: Throughout life, stem cells make new cells in various tissues. Bulge region of hair follicle indicated as sources of stem cells for along times but little studies done in vitro to characterize rat bulge hair follicle stem cells ...
آسالگو, سارا, نوبخت, ملیحه, نجف زاده, نوروز   +2 more
core  

LncRNAs in Secondary Hair Follicle of Cashmere Goat: Identification, Expression, and Their Regulatory Network in Wnt Signaling Pathway

Animal Biotechnology, 2017
Long noncoding RNAs (lncRNAs) are a novel class of eukaryotic transcripts. They are thought to act as a critical regulator of protein-coding gene expression. Herein, we identified and characterized 13 putative lncRNAs from the expressed sequence tags from secondary hair follicle of Cashmere goat.
Wen L, Bai, Su J, Zhao, Ze Y, Wang, Yu B, Zhu, Yun L, Dang, Yu Y, Cong, Hui L, Xue, Wei, Wang, Liang, Deng, Dan, Guo, Shi Q, Wang, Yan X, Zhu, Rong H, Yin   +12 more
openaire   +2 more sources

Single‐Nucleus Transcriptomic Atlas of Human Vellus Hair Pilosebaceous Units Reveals Age‐Associated Remodeling

Advanced Science, EarlyView.
Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li, Zhuoqiong Qiu, Xiaoyu Pan, Geyang Xu, Shanshan Peng, Ronghui Zhu, Qiuyang Luo, Xiaokai Fang, Xu Yao, Wei Li   +9 more
wiley   +1 more source

List of hair follicle-associated genes.

, 2016
List of hair follicle-associated genes.
Shin Yamada (425231), Masaya Seki (2583376), Hideyuki J. Majima (2583379), Chiaki Mukai (808157), Noriaki Ishioka (796824), Masahiro Terada (153057), Akira Higashibata (350426), Rika Takahashi (2583373), Masamichi Sudoh (2583370)   +8 more
core   +1 more source

Self‐Adaptive Biomimetic Nanocomposite Hydrogel Orchestrates Dual‐Targeting and On‐Demand H2S Gasotransmission for Multifactorial Diabetic Wound Therapy

Advanced Science, EarlyView.
A self‐adaptive and biomimetic nanocomposite hydrogel is engineered to orchestrate dual‐targeting and on‐demand H2S gasotransmission for multifactorial diabetic wound therapy. By seamlessly integrating antibacterial, antioxidant, anti‐inflammatory, immunoregulatory, and pro‐angiogenic functions within a single platform, this hydrogel dynamically ...
Kefan Wu, Xiaoxue Yang, Yonghang Liu, Yi Xiao, Shiyu Meng, Ao Li, Yi Zhun Zhu, Hui Guo, Xiaolin Wang   +8 more
wiley   +1 more source

Neurotrophic Effects of Silibinin on Differentiation of Hair Follicle Stem Cells to Neurons [PDF]

Neurotrophic Effects of Silibinin on Differentiation of Hair Follicle Stem Cells to NeuronsAbstract Background and Objectives: Hair Follicle Bulge region due to its availability and abundance is one of the areas which is easily accessible to Multi-potent
آسالگو, سارا, کردستانی شرق, بهاره, نوبخت, ملیحه, رهبر روشندل, ناهید, نجف زاده, نوروز, موسوی زاده, کاظم   +5 more
core  

Targeting Macrophage STING O‐GlcNAcylation via Small‐Molecule Allosteric Modulation for Psoriasis Therapy

Advanced Science, EarlyView.
Paeoniflorin allosterically targets the STING cyclic dinucleotide‐binding domain, stabilizes an inactive open conformation, and disrupts STING–OGT interaction to reduce Thr229 O‐GlcNAcylation and downstream signaling. This mechanism restrains myeloid STING activation, alleviates psoriasis‐like inflammation, and is supported by analyses of patient ...
Fang‐Fang Zhuo, Cheng‐Chen Hou, Wei Wang, Ya‐Xuan Zhu, Ling Li, Li‐Juan Liu, Chuan‐Jian Lu, Peng‐Fei Tu, Yang Liu, Rui‐Zhi Zhao, Ke‐Wu Zeng   +10 more
wiley   +1 more source

Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers

PLOS ONE, 2016
Precision genetic engineering accelerates the genetic improvement of livestock for agriculture and biomedicine. We have recently reported our success in producing gene-modified goats using the CRISPR/Cas9 system through microinjection of Cas9 mRNA and sgRNAs targeting the MSTN and FGF5 genes in goat embryos.
Xiaolong Wang, Bei Cai, Jiankui Zhou, Haijing Zhu, Yiyuan Niu, Baohua Ma, Honghao Yu, Anmin Lei, Hailong Yan, Qiaoyan Shen, Lei Shi, Xiaoe Zhao, Jinlian Hua, Xingxu Huang, Lei Qu, Yulin Chen   +15 more
openaire   +4 more sources

Phase‐Programmed Microneedles Enable Sequential Hydrogen and Quercetin Release for Scar‐Reduced Regeneration of Burn Wounds

Advanced Science, EarlyView.
A phase‐programmed microneedle patch, comprising a poly (lactic‐co‐glycolic acid) (PLGA) shell and a sulfobutylether‐β‐cyclodextrin (SBECD) core, is designed for sequential hydrogen and quercetin release for scar‐reduced regeneration of burn wounds. ABSTRACT Burn wounds complicated by bacterial infection and fibrotic scarring remain a major clinical ...
Yongnian Zeng, Zhigang Chu, Huiyuan Yang, Wen Zhang, Peng Jiang, Jiapeng Lei, Siyu Zhang, Qiongfang Ruan, Shuhua Liu, Wei Li   +9 more
wiley   +1 more source

Early stages of tooth development in the harbor porpoise Phocoena phocoena

The Anatomical Record, EarlyView.
Abstract Here we describe the stages of tooth development in toothed whales on the basis of the harbor porpoise (Phocoena phocoena). The aim of the study was to find out whether these stages are identical to those of other mammals analyzed so far although toothed whales are homodont and monophyodont.
Lasse M. Mathes, Lennart Müller‐Thomsen, Stefan Huggenberger   +2 more
wiley   +1 more source