Results 41 to 50 of about 3,631,955 (312)

A case report of coinfection of cytomegalovirus colitis and tuberculosis of the intestine in an older patient with heterozygous beta-thalassemia-induced immunodeficiency

Journal of the Indian Academy of Geriatrics, 2021
While thalassemia major is a known immunodeficient state, reports of thalassemia minor presenting with immunodeficiency are rare. We present a 66-year-old male with acute abdomen, hemorrhagic colitis, and septic shock.
Sunny Singhal, Gaurav Desai, Aparajit Ballav Dey   +2 more
doaj   +1 more source

Risk factors for severe infections in secondary immunodeficiency: a retrospective US administrative claims study in patients with hematological malignancies

Leukemia and Lymphoma, 2021
Real-world data are lacking to identify patients with secondary immunodeficiency (SID) who may benefit most from anti-infective interventions. This retrospective analysis used the IQVIA PharMetrics® Plus database to assess baseline characteristics ...
S. Jolles, B. Smith, D. Vinh, R. Mallick, Gabriela Espinoza, M. DeKoven, V. Divino   +6 more
semanticscholar   +1 more source

Facilitated subcutaneous immunoglobulin use in pediatric patients with primary or secondary immunodeficiency diseases.

Immunotherapy, 2021
Aim: While facilitated subcutaneous immunoglobulin (fSCIG) has been evaluated in pediatric patients with primary immunodeficiency diseases in clinical trials, real-world data are lacking. Materials & methods: This multicenter, retrospective, chart review
U. Baumann, M. Fasshauer, C. Pausch, H. Wittkowski, Corinna Hermann, D. Pittrow, M. Borte   +6 more
semanticscholar   +1 more source

Vaccination in Patients with Chronic Lymphocytic Leukemia: Current Problems

Эпидемиология и вакцинопрофилактика, 2021
Relevance. Infections are the most common complication of chronic lymphocytic leukemia (CLL). According to registry studies, infections are the cause of death in 10–20% of patients.
M. I. Kislova, A. A. Petrenko, M. P. Kostinov, E. A. Nikitin   +3 more
doaj   +1 more source

Infections in secondary immunodeficiency patients treated with Privigen® or Hizentra®: a retrospective US administrative claims study in patients with hematological malignancies

Leukemia and Lymphoma, 2021
B cell-derived lymphoproliferative disorders are associated with secondary immunodeficiency (SID); some patients require immunoglobulin replacement therapy (IgRT) to mitigate infections.
R. Mallick, V. Divino, B. Smith, S. Jolles, M. DeKoven, D. Vinh   +5 more
semanticscholar   +1 more source

Primary HIV-1 Infection Among Infants in sub-Saharan Africa: HPTN 024. [PDF]

, 2009
Our objectives were to assess clinical signs and diagnoses associated with primary HIV-1 infection among infants. We analyzed data from a clinical trial (HIV Prevention Trials Network Protocol 024) in sub-Saharan Africa.
Anthony Mwatha, Barbra Richardson, Bollinger, Boom, Chasela, Daar, Guay, Hecht, Horwood, Irving Hoffman, Jennifer S Read, Jones, Kahn, Karim Manji, Kinloch-de Loes, Lavreys, Lepage, Lynda Emel, Megan Valentine, Nozyce, Richardson, Robert L Goldenberg, Rouet, Schacker, Taha, Taha E Taha, Usha Sharma   +26 more
core   +2 more sources

Immunodeficiency secondary to anticytokine autoantibodies [PDF]

Current Opinion in Allergy & Clinical Immunology, 2010
Anticytokine autoantibodies are an important and emerging mechanism of disease pathogenesis. We will review the clinical and laboratory features of syndromes in which immunodeficiency is caused by or associated with neutralizing anticytokine autoantibodies.A growing number of patients have been described who demonstrate unique infectious phenotypes ...
Sarah K, Browne, Steven M, Holland
openaire   +2 more sources

Conserved presence of G-quadruplex forming sequences in the Long Terminal Repeat Promoter of Lentiviruses [PDF]

, 2017
G-quadruplexes (G4s) are secondary structures of nucleic acids that epigenetically regulate cellular processes. In the human immunodeficiency lentivirus 1 (HIV-1), dynamic G4s are located in the unique viral LTR promoter.
A Ayouba, A Henderson, A Rambaut, AK Todd, AM Fleming, AN Lane, AR Haeusler, B Berkhout, B Zhou, BF Keele, D Piekna-Przybylska, D Qu, D Rhodes, D Sen, DJ Patel, E Tosoni, EA Raiber, F Barre-Sinoussi, F Benachenhou, F Bibollet-Ruche, F Heuverswyn Van, F Turrini, G Biffi, GE Crooks, IT Holder, J Felsenstein, J Norseen, J Qiu, J Song, J Yamaguchi, JE Clements, JF Fisette, JP Taylor, K Tamura, K Tluckova, KA Jones, LA Pereira, M Fry, M Metifiot, M Sala, M Scalabrin, MA Larkin, N Maizels, ND Perkins, NH Campbell, P Fratta, P Ivanov, P Murat, P Sket, R Perrone, R Perrone, R Perrone, R Perrone, RC Edgar, RC Gallo, RJ Gifford, S Amrane, S Artusi, S Artusi, S Balasubramanian, S Bhatia, S Broos, S Burge, S Pohlmann, SE Tong-Starksen, SR Wang, SR Wang, Y Wang   +67 more
core   +1 more source

Evaluation of the 10 Warning Signs in Primary and Secondary Immunodeficient Patients

Frontiers in Immunology, 2022
ObjectivesTen warning signs of primary immunodeficiency (PID) were suggested by the Jeffrey Modell Foundation (JMF), to increase physician awareness of PID. These warning signs have not yet been evaluated for patients with secondary immunodeficiency (SID)
Fadime Ceyda Eldeniz, Yahya Gul, Alaaddin Yorulmaz, Sukru Nail Guner, Sevgi Keles, Ismail Reisli   +5 more
doaj   +1 more source

Gastric cancer is the leading cause of death in Italian adult patients with common variable immunodeficiency [PDF]

, 2018
An increased prevalence of malignant lymphoma and of gastric cancer has been observed in large cohorts of patients with common variable immunodeficiency (CVID), the most frequently symptomatic primary immunodeficiency. Surveillance strategies for cancers
Agostini, Carlo, Cinetto, Francesco, Crescenzi, Ludovica, Milito, Cinzia, Pecoraro, Antonio, Pulvirenti, Federica, Quinti, Isabella, Rizzo, Francesca, Santangeli, Enrico, Spadaro, Giuseppe, Tabolli, Stefano, Valente, Michele   +11 more
core   +3 more sources