Results 171 to 180 of about 54,801 (253)

Spirulina platensis and β-glucan mitigate cyclophosphamide-induced Immunosuppression in broilers: Differential effects of preventive and therapeutic strategies via redox-inflammatory modulation. [PDF]

Poult Sci
Elshaitany KAM, Mokhbatly AA, Ghazy EW, ELazab MFA, Shukry M, Assar DH.   +5 more
europepmc   +1 more source

The lung is more than an organ of gas exchange: immunocompetency, platelets and implications for drug discovery

British Journal of Pharmacology, EarlyView.
Abstract The lungs have for a long time been recognised as having pharmacological significance as a specific organ to modulate the pharmacokinetics of endogenous substances needed to maintain homeostasis. The lungs are therefore the site of action of certain drugs that act on these homeostatic processes, resulting in systemic effects on the ...
Simon C. Pitchford
wiley   +1 more source

Cryoglobulinemia, monoclonal and mixed cryoglobulinemia syndromes, cryoglobulinemic vasculitis: <i>a proposal for comprehensive nomenclature and definition</i>. [PDF]

Front Immunol
Ferri C, Gragnani L, Zignego AL, Giuggioli D.   +3 more
europepmc   +1 more source

Integrated Engineering of CAR‐T Cells for Solid Tumours

Cell Proliferation, EarlyView.
Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang, Tan Li, Ping He, Zhijie Zhao, Shenglong Li, Liming Wang   +5 more
wiley   +1 more source

Molecular characterization and tissue tropism of an Iraqi field isolate of fowl adenovirus serotype 8a in broiler chickens. [PDF]

PLoS One
Hamad MA, Alfahdawi AJ, Manswr BM.
europepmc   +1 more source

Primary Cutaneous Gamma‐Delta T‐Cell Lymphoma Complicating Long‐Standing Immunosuppressed Dermatomyositis

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Primary cutaneous gamma‐delta T‐cell lymphoma (PCGD‐TCL) is a rare cytotoxic lymphoma with key oncogenic drivers in the JAK/STAT pathway. Also primarily involving the subcutaneous adipose tissue, subcutaneous panniculitis‐like T‐cell lymphoma (SPTCL) is more frequently encountered in scenarios of autoimmune disorders.
Bennett Christie‐Nguyen, Youn H. Kim, David F. Fiorentino, Danielle Tartar, Ryanne Brown, Robert A. Novoa, Kerri E. Rieger   +6 more
wiley   +1 more source

A Human-Based Skin-Lymphoreticular Model-on-Chip to Emulate Inflammatory Skin Conditions. [PDF]

Adv Healthc Mater
Tan Z, Adhikary PP, Wörz D, Hedtrich S.
europepmc   +1 more source

Lymphoid Organ Architecture and Hematopoiesis Disruption in Spinal Muscular Atrophy: Therapeutic Rescue by SMN Restoration. [PDF]

Int J Mol Sci
Guillamón P, Lindner G, Guillen J, Gatius A, Gras S, Martínez-España L, Piedrafita L, Panosa A, Tapia O, Mora C, Esquerda JE, Tizzano EF, Tarabal O, Calderó J.   +13 more
europepmc   +1 more source

Post‐Transplant Bendamustine as a Platform for Immune Modulation After Allogeneic Hematopoietic Cell Transplantation

European Journal of Haematology, EarlyView.
ABSTRACT Post‐transplant cyclophosphamide (PT‐CY) remains the standard of care for graft‐versus‐host disease (GvHD) prophylaxis in haploidentical hematopoietic cell transplantation (HCT), yet relapse, delayed immune reconstitution, infections, and organ toxicity represent persistent and clinically meaningful limitations.
Megan J. Cracchiolo, Richard J. Simpson, Emmanuel Katsanis   +2 more
wiley   +1 more source

Comparative pathogenicity of very virulent and novel variant infectious bursal disease virus Egyptian strains in chickens. [PDF]

Virol J
Ibrahim M, Ayman D, Arafa W, Abdelmagid MA, El-Sanousi AA, Shaheen M.   +5 more
europepmc   +1 more source