Results 181 to 190 of about 57,576 (254)

Irradiation‐Induced CD62L Shedding in Human Plasmacytoid Dendritic Cells Depends on ADAM17 and p38 MAPK

Immunology, EarlyView.
Human plasmacytoid dendritic cell‐based vaccines efficiently migrate from blood to lymph nodes and prime naive T cells in humanised mice. Irradiation‐induced CD62L shedding, mediated by p38 MAP kinase and ADAM17, is involved in the regulation of PDC migration to secondary lymphoid organs in this model.
Estelle Leplus, Jamila Kacher, Dalil Hannani, Guillaume Vayssiere, Jean‐Paul Molens, Karine Laulanier, Dan Georgess, Véronique Josserand, Philippe Saas, Séverine Planel, Laurence Chaperot, Joel Plumas   +11 more
wiley   +1 more source

Spatiotemporal orchestration of the salivary gland immune microenvironment in Sjögren's disease: a multidimensional framework of epithelial licensing, lymphoid neogenesis, and stromal remodeling. [PDF]

Front Immunol
Ren S, Li Q, Niu R, Liu X, Zhou P, Yang X, Liang H.   +6 more
europepmc   +1 more source

Linoleic Acid Enhances Murine Natural Killer Cell Function In Vitro but Compromises Mitochondrial Bioenergetic Function During Retroviral Infection

Immunology, EarlyView.
Natural Killer (NK) cells are potent effectors against virus‐infected and tumour cells. During Friend Virus (FV) infection, fatty acid metabolism supports NK‐cell effector functions. Here, we found that NK cells from FV‐infected mice preferentially take up linoleic acid (LA), which reduced proliferation, mitochondrial function, and increased reactive ...
Vaasudevan Sridhar, Simone Schimmer, Tanja Werner, Rachel Giesen, Mohamed Saad, Constantin P. Krempe, Sven W. Meckelmann, Ulf Dittmer, Elisabeth Littwitz‐Salomon   +8 more
wiley   +1 more source

<i>KCTD5::PDGFRB</i> Fusion Gene Leading to Clonal Hypereosinophilia With Cardiac Involvement in a Young Adult: A Case Report. [PDF]

Case Rep Hematol
de Groote L, Papazoglou D, Ku J, Heimann P, Dewispelaere L, Sidon P, Roufosse F, Trépant AL, Cilla N.   +8 more
europepmc   +1 more source

Challenging Host Specificity: Malacosporean Parasite Dynamics—Tetracapsuloides bryosalmonae Beyond Salmonids—An Infection Experiment

Journal of Fish Diseases, EarlyView.
ABSTRACT Proliferative Kidney Disease (PKD) is a severe parasitic disease of salmonids caused by the malacosporean endoparasite Tetracapsuloides bryosalmonae. In the fish intermediate host, the parasite is disseminated via the circulatory system and ultimately reaches the kidney, where it matures before releasing infective spores into the environment ...
Céline Möckli, Nicolas Diserens, Gary Delalay, Gastón Moré, Heike Schmidt‐Posthaus   +4 more
wiley   +1 more source

The Developmental and Functional Implications of Age-Associated B Cells (ABCs) Across Tissue Microenvironments. [PDF]

Immunol Rev
Francis RL, Weinstein JS.
europepmc   +1 more source

Disseminated Cryptococcosis under Fingolimod Therapy

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Sven C. Engler, Morna F. Schmidt, Ana Ortins‐Pina, David Kluwig, Amir S. Yazdi   +4 more
wiley   +1 more source

Assessing mature and immature collagen in tonsillar tissue using second harmonic generation microscopy

Journal of Microscopy, EarlyView.
Abstract Recurrent tonsillitis (RT) and obstructive sleep apnoea (OSA) are major indications for tonsillectomy, yet their tissue‐level pathology remains unclear. Recurrent inflammation in RT may induce collagen remodelling through excess extracellular matrix deposition.
Kay Polland, Megan Clapperton, Thushitha Kunanandam, Catalina D Florea, Catriona M Douglas, Gail McConnell   +5 more
wiley   +1 more source

Stepwise Evolution of Immunodeficient Mouse Models: Focus on NCG Strains and Their Applications in Humanized Immune System Research. [PDF]

Vaccines (Basel)
Sun H, Fan J, Zhang Y, Xing J, Zhang Y, Ju C, Liang J.   +6 more
europepmc   +1 more source