Results 281 to 290 of about 182,231 (346)

Genomic Ascertainment of CHEK2-Related Cancer Predisposition.

JAMA Netw Open
Kim SY, Kim J, Ramos M, Haley J, Smelser D, Rao HS, Mirshahi UL, Nathanson KL, Graubard BI, Katki HA, Carey D, Stewart DR, Geisinger-Regeneron DiscovEHR Collaboration and Penn Medicine Biobank.   +12 more
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Cytokine regulation of secondary lymphoid organ development

Current Opinion in Immunology, 1998
Lymphotoxin and tumor necrosis factor provide essential signals for the formation of secondary lymphoid tissue structures. Lymphotoxin in its membrane form (LT alpha 1 beta 2 heterotrimer) is required for the development of lymph nodes and Peyer's patches and supports the development of normal spleen structure.
D D, Chaplin, Y, Fu
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Modeling immune reactivity in secondary lymphoid organs

Bulletin of Mathematical Biology, 1992
Models of the dynamical interactions important in generating immune reactivity have generally assumed that the immune system is a single well-stirred compartment. Here we explicitly take into account the compartmentalized nature of the immune system and show that qualitative conclusions, such as the stability of the immune steady state, depend on ...
Perelson, Alan S., Weisbuch, Gérard
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Chemokines as organizers of primary and secondary lymphoid organs

Seminars in Immunology, 2003
Lymphoid organs represent highly specialized tissues enabling the development and activation of B and T lymphocytes. Contact between lymphoid and parenchymal cells in bone marrow and thymus is a prerequisite for proper development of B and T cells, respectively, while secondary lymphoid organs, such as spleen and lymph nodes are the places where B and ...
Lars, Ohl, Günter, Bernhardt, Oliver, Pabst, Reinhold, Förster   +3 more
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Distinct activities of p52/NF-kappa B required for proper secondary lymphoid organ microarchitecture: functions enhanced by Bcl-3.

Journal of Immunology, 1999
Mice rendered deficient in p52, a subunit of NF-kappa B, or in Bcl-3, an I kappa B-related regulator that associates with p52 homodimers, share defects in the microarchitecture of secondary lymphoid organs.
L. Poljak, Louise Carlson, Kirk Cunningham, Marie Kosco-Vilbois, U. Siebenlist   +4 more
semanticscholar   +1 more source

Lymphocyte tracking and interactions in secondary lymphoid organs

Inflammation Research, 2007
The induction of an adaptive immune response is an essential step in the generation of long-lasting, protective immunity to pathogens. Many studies over the last few decades have identified the cell populations involved in the generation of antigen-specific immunity and elucidated the role of many important molecules.
Millington, O.R., Zinselmeyer, B.H., Brewer, J.M., Garside, P., Rush, C.M.   +4 more
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Artificial Engineering of Secondary Lymphoid Organs

2010
Secondary lymphoid organs such as spleen and lymph nodes are highly organized immune structures essential for the initiation of immune responses. They display distinct B cell and T cell compartments associated with specific stromal follicular dendritic cells and fibroblastic reticular cells, respectively. Interweaved through the parenchyma is a conduit
Jonathan K H, Tan, Takeshi, Watanabe
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