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Secondary metabolism in simulated microgravity

The Chemical Record, 2001
AbstractWe have studied microbial secondary metabolism in a simulated microgravity (SMG) environment provided by NASA rotating‐wall bioreactors (RWBs). These reactors were designed to simulate some aspects of actual microgravity that occur in space. Growth and product formation were observed in SMG in all cases studied, i.e., Bacillus brevis produced ...
Aiqi Fang, Arnold L. Demain
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What is Secondary Metabolism?

1984
In addition to the primary metabolic reactions which are similar in all groups of living organisms (formation and breakdown of nucleic acids and proteins and their precursors, of most carbohydrates, of some carboxylic acids, etc., cf. Table 6), a vast number of metabolic pathways lead to the formation of peculiar chemical compounds, the so-called ...
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SECONDARY METABOLISM AS DIFFERENTIATION

Journal of Food Safety, 1983
Secondary metabolism is the biosynthesis, transformation, and degradation of a wide array of natural products. These low molecular weight organic compounds are generally produced at a restricted phase of the life cycle, often in association with differentiated morphological structures.
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Adventitious Roots and Secondary Metabolism

Chinese Journal of Biotechnology, 2008
Plants are a rich source of valuable secondary metabolites and in the recent years plant cell, tissue and organ cultures have been developed as an important alternative sources for the production of these compounds. Adventitious roots have been successfully induced in many plant species and cultured for the production of high value secondary ...
Kee-Yoeup Paek   +2 more
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Biochemistry of Secondary Metabolism in Plants

2023
Through secondary or specialized metabolites plants adapt to their environment. A myriad of different compounds plays a significant role in the plant–environment interaction. These compounds help plants in attracting pollinators or deterring herbivores, in their protection from pathogen microorganisms, or in protection from various abiotic stresses ...
Rajčević, Nemanja   +3 more
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Secondary Metabolism in Myxobacteria

2014
In the past 30 years myxobacteria have been established as proficient producers of various secondary metabolites and are regarded today as one of the few important sources for microbial natural products besides actinomycetes and fungi. Epothilone from Sorangium cellulosum recently successfully finished phase III clinical trials as an anticancer agent ...
Rolf Müller, Helge B. Bode
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Transcriptional regulation of secondary metabolism

Functional Plant Biology, 2003
Plants produce secondary metabolites during development and in response to environmental stimuli such as light or pathogen attack. Transcriptional regulation provides the most important control point for the secondary metabolic pathways studied to date. In this article we review the data on the transcription factors that modulate this regulation.
Kevin M. Davies, Kathy E. Schwinn
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Microbial secondary metabolism

Trends in Biochemical Sciences, 1980
Abstract Microbial products (e.g. pigments, alkaloids, toxins, antibiotics, gibberellins, carotenoids, etc.) that serve no obvious function in the life of organisms that produce them, are called secondary metabolites. The production of secondary metabolites is not universal among microbes.
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Metabolic engineering of the plant primary–secondary metabolism interface

Current Opinion in Biotechnology, 2011
Plants synthesize a myriad of secondary metabolites (SMs) that are derived from central or primary metabolism. While these so-called natural products have been targets for plant metabolic engineering attempts for many years, the immense value of manipulating the interface between committed steps in secondary metabolism pathways and those in primary ...
Asaph Aharoni, Gad Galili
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Metabolic Engineering of Secondary Plant Metabolism

2017
Metabolic engineering is a modulation of metabolic pathway(s) of the host either to increase the concentration of existing compounds or to produce a novel compound. It began with the engineering of microorganisms, and the concept has been extrapolated to plants opening newer promising perspectives.
Malik Zainul Abdin   +3 more
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