Results 61 to 70 of about 1,364,633 (308)

Functional characterization of HMG_9 and C2H2.07 as positive regulators of ganoderic acid biosynthesis in Ganoderma lucidum

Microbial Cell Factories
Background Ganoderic acids (GAs) are high-value lanostane-type triterpenoids produced by Ganoderma lucidum (G. lucidum) and are responsible for its diverse pharmacological activities. Previous studies have elucidated key enzymatic steps of the mevalonate
Yihong Li, Miaoqing Li, Liwei Liu, Wan Yang, Jihong Yang, Wei Li, Rui Zhang, Zongqi Yang, Zongsuo Liang, Zhenhao Li, Dongfeng Yang   +10 more
doaj   +1 more source

Genome-wide identification and characterization of phased small interfering RNA genes in response to Botrytis cinerea infection in Solanum lycopersicum

Scientific Reports, 2017
Phased small interfering RNAs (phasiRNAs) are encoded by a novel class of genes known as phasiRNA producing (PHAS) genes. These genes play important regulatory roles by targeting protein coding transcripts in plant species. In this study, 91 regions were
Fangli Wu, Yue Chen, Xing Tian, Xiaole Zhu, Weibo Jin   +4 more
doaj   +1 more source

The complete chloroplast genome sequence of Japanese buttercup Ranunculus japonicus Thunb.

Mitochondrial DNA. Part B. Resources, 2021
Ranunculus japonicus is an important medicinal herb widely used in East Asia. In this study, we report the first complete chloroplast genome sequence of Ranunculus japonicus using next-generation sequencing technology.
Wen-Qiong Zeng, Hua-Jian Yan, Yun-Zhe Wu, Rui-rui Wang, Xian-Fei Xiao, Zhe-Chen Qi, Xiao-Ling Yan   +6 more
doaj   +1 more source

Analysis of the Changes in the Oxidation of Brain Tissue Cytochrome-c-Oxidase in Traumatic Brain Injury Patients during Hypercapnoea A Broadband NIRS Study [PDF]

, 2011
Using broadband near-infrared spectroscopy (NIRS) and cerebral micro-dialysis (MD), we investigated cerebral cellular metabolism and mitochondrial redox states, following hypercapnoea in 6 patients with traumatic brain injury (TBI).
Elwell, CE, Ghosh, A, Leung, TS, Pritchard, C, Smith, M, Tachtsidis, I, Tisdall, MM   +6 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Transcriptome profiling of a novel Enterobacter aerogenes mutant with mannose-rich exopolysaccharide phenotype induced by phosphoenolpyruvate carboxylase inactivation

Applied and Environmental Microbiology
Mannose, a common monosaccharide with primary functions in protein glycosylation and immune regulation, has been widely used in medicine, cosmetics, and food additives, increasing its economic value.
Xinru Peng, Jiale Chen, Yilin Ding, Ruoxuan Bai, Ping Lu, Fangxu Xu, Guohong Zeng, Hongxin Zhao   +7 more
doaj   +1 more source

Molecular phenotyping of the pal1 and pal2 mutants of Arabidopsis thaliana reveals far-reaching consequences on phenylpropanoid, amino acid, and carbohydrate metabolism [PDF]

, 2004
The first enzyme of the phenylpropanoid pathway, Phe ammonia-lyase (PAL), is encoded by four genes in Arabidopsis thaliana. Whereas PAL function is well established in various plants, an insight into the functional significance of individual gene family ...
Boerjan, Wout, De Rycke, Riet, Goeminne, Geert, Hostyn, Vanessa, Joseleau, Jean-Paul, Kushnir, Sergei, Messens, Eric, Morreel, Kris, Ralph, John, Rohde, Antje, Van Beeumen, Jozef, Van Doorsselaere, Jan, Van Driessche, Gonzalez, Vuylsteke, Marnik   +13 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Mr-lac3 and Mr-lcc2 in Metarhizium robertsii Regulate Conidiation and Maturation, Enhancing Tolerance to Abiotic Stresses and Pathogenicity

Journal of Fungi
As a type of multicopper oxidase, laccases play multiple biological roles in entomopathogenic fungi, enhancing their survival, development, and pathogenicity. However, the mechanisms by which laccases operate in these fungi remain under-researched.
Qiaoyun Wu, Yingying Ye, Yiran Liu, Yufan He, Xing Li, Siqi Yang, Tongtong Xu, Xiufang Hu, Guohong Zeng   +8 more
doaj   +1 more source

Metabolic Engineering of Enterobacter aerogenes for Improved 2,3-Butanediol Production by Manipulating NADH Levels and Overexpressing the Small RNA RyhB

Frontiers in Microbiology, 2021
Biotechnological production of 2,3-butanediol (2,3-BD), a versatile platform bio-chemical and a potential biofuel, is limited due to by-product toxicity.
Yan Wu, Yan Wu, Wanying Chu, Jiayao Yang, Yudong Xu, Qi Shen, Haoning Yang, Fangxu Xu, Yefei Liu, Ping Lu, Ke Jiang, Hongxin Zhao   +11 more
doaj   +1 more source