Results 71 to 80 of about 1,364,633 (308)

Induction of microbial secondary metabolism [PDF]

, 2010
Precursors often stimulate production of secondary metabolites either by increasing the amount of a limiting precursor, by inducing a biosynthetic enzyme (synthase) or both.
Arnold L. Demain
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Abiotic stress-induced changes in Tetrastigma hemsleyanum: insights from secondary metabolite biosynthesis and enhancement of plant defense mechanisms

BMC Plant Biology
Tetrastigma hemsleyanum, a traditional Chinese medicinal plant with anti-inflammatory, anti-cancer, and anti-tumor properties, faces increasing abiotic stress due to climate change, agricultural chemicals, and industrialization.
Minmin Chen, Xiaoqun Wang, Xiawen Zhou, Baiyu Huang, Yujie Zhao, Haiying Liu, Qiuling He   +6 more
doaj   +1 more source

Screening out Biomarkers of Tetrastigma hemsleyanum for Anti-Cancer and Anti-Inflammatory Based on Spectrum-Effect Relationship Coupled with UPLC-Q-TOF-MS

Molecules, 2023
Tetrastigma hemsleyanum Diels et Gilg. (T. hemsleyanum) is an economically and medicinally valuable species within the genus Tetrastigma. However, the material basis of its pharmacological action and the biomarkers associated with its anti-cancer and ...
Jie Xia, Xiuyue Li, Min Lin, Jiani Yu, Zhongda Zeng, Fei Ye, Guanjun Hu, Qiang Miu, Qiuling He, Xiaodan Zhang, Zongsuo Liang   +10 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Succession of physiological stages hallmarks the transcriptomic response of the fungus Aspergillus niger to lignocellulose. [PDF]

, 2020
BackgroundUnderstanding how fungi degrade lignocellulose is a cornerstone of improving renewables-based biotechnology, in particular for the production of hydrolytic enzymes.
Archer, David B, Arvas, Mikko, Barry, Kerrie W, Blythe, Martin J, Chan, Leanne Jade G, Daly, Paul, Delmas, Stéphane, Gaddipati, Sanyasi, Grigoriev, Igor V, Ibbett, Roger, Kokolski, Matt, Lindquist, Erika, Lipzen, Anna, Ngan, Chew Yee, Petzold, Christopher J, Pullan, Steven T, Raulo, Roxane, Simmons, Blake A, Singan, Vasanth R, Tucker, Gregory A, van Munster, Jolanda M   +20 more
core  

The Origin, Succession, and Predicted Metabolism of Bacterial Communities Associated with Leaf Decomposition. [PDF]

, 2019
Intraspecific variation in plant nutrient and defensive traits can regulate ecosystem-level processes, such as decomposition and transformation of plant carbon and nutrients.
Gilbert, Jack A, Jackrel, Sara L, Wootton, J Timothy   +2 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The complete chloroplast genome of endangered Zhangjiajie sage Salvia daiguii Y. K. Wei & Y. B. Huang (Lamiaceae)

Mitochondrial DNA. Part B. Resources, 2020
The complete chloroplast genome of Zhangjiajie sage, Salvia daiguii, was assembled in this study. The genome is 151,434 bp in length and contained 134 encoded genes in total, including 88 protein-coding genes, eight ribosomal RNA genes, and 37 transfer ...
Xuan Zhou, Yan-Bo Huang, Zhi-Cheng Zhang, Xin-Yan Xu, Rui-Hong Wang, Ling Xu, Zhe-Chen Qi, Yu-Kun Wei   +7 more
doaj   +1 more source

The complete chloroplast genome of Pleione hookeriana (Orchidaceae) from Yunnan Province, China

Mitochondrial DNA. Part B. Resources, 2022
Pleione hookeriana (Lindl.) B. S. Williams is a species of Orchidaceae with high ornamental value. It is a protected plant in China. To document the genetic history of this rare species, the chloroplast genome sequence of P.
Weiguo Chai, Xiang Chen, Huimin Li, Pengguo Xia   +3 more
doaj   +1 more source