Results 11 to 20 of about 3,541,226 (351)

Melatonin alters the secondary metabolite profile of grape berry skin by promoting VvMYB14-mediated ethylene biosynthesis

open access: yesHorticulture Research, 2021
The interplay between melatonin and ethylene in the regulation of fruit metabolism and the underlying molecular mechanism of this interplay remain largely unclear. Here, widely targeted metabolomics analysis revealed a total of 464 metabolites present in
Wanyun Ma   +5 more
semanticscholar   +1 more source

Transcriptome and translatome profiles of Streptomyces species in different growth phases. [PDF]

open access: yes, 2020
Streptomyces are efficient producers of various bioactive compounds, which are mostly synthesized by their secondary metabolite biosynthetic gene clusters (smBGCs).
Cho, Byung-Kwan   +6 more
core   +1 more source

Systems and synthetic biology to elucidate secondary metabolite biosynthetic gene clusters encoded in Streptomyces genomes.

open access: yesNatural product reports (Print), 2021
Covering: 2010 to 2020Over the last few decades, Streptomyces have been extensively investigated for their ability to produce diverse bioactive secondary metabolites. Recent advances in Streptomyces research have been largely supported by improvements in
Namil Lee   +10 more
semanticscholar   +1 more source

Aspergillus niger as a Secondary Metabolite Factory

open access: yesFrontiers in Chemistry, 2021
Aspergillus niger, one of the most common and important fungal species, is ubiquitous in various environments. A. niger isolates possess a large number of cryptic biosynthetic gene clusters (BGCs) and produce various biomolecules as secondary metabolites
Ronglu Yu   +4 more
semanticscholar   +1 more source

Comprehensive prediction of secondary metabolite structure and biological activity from microbial genome sequences

open access: yesNature Communications, 2020
Novel antibiotics are urgently needed to address the looming global crisis of antibiotic resistance. Historically, the primary source of clinically used antibiotics has been microbial secondary metabolism.
M. Skinnider   +15 more
semanticscholar   +1 more source

Thirty complete Streptomyces genome sequences for mining novel secondary metabolite biosynthetic gene clusters

open access: yesScientific Data, 2020
Streptomyces are Gram-positive bacteria of significant industrial importance due to their ability to produce a wide range of antibiotics and bioactive secondary metabolites. Recent advances in genome mining have revealed that Streptomyces genomes possess
Namil Lee   +6 more
semanticscholar   +1 more source

antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline

open access: yesNucleic Acids Res., 2019
Secondary metabolites produced by bacteria and fungi are an important source of antimicrobials and other bioactive compounds. In recent years, genome mining has seen broad applications in identifying and characterizing new compounds as well as in ...
K. Blin   +7 more
semanticscholar   +1 more source

Metabolomics - what nomenclature to use?

open access: yesEcocycles, 2017
This Opinion paper was written to initiate a discussion on the nomenclature used in metabolomic studies. The paper is based on the belief that the currently used classification of metabolites as "primary" and "secondary" are inaccurate and somewhat ...
Tamas Komives
doaj   +1 more source

Metabolomics for Secondary Metabolite Research

open access: yesMetabolites, 2013
Metabolomics, the global characterization of metabolite profiles, is becoming an increasingly powerful tool for research on secondary metabolite discovery and production.
Eriko Takano   +3 more
doaj   +1 more source

Engineering of Streptomyces lividans for heterologous expression of secondary metabolite gene clusters

open access: yesMicrobial Cell Factories, 2020
BackgroundHeterologous expression of secondary metabolite gene clusters is used to achieve increased production of desired compounds, activate cryptic gene clusters, manipulate clusters from genetically unamenable strains, obtain natural products from ...
Yousra Ahmed   +5 more
semanticscholar   +1 more source

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