Coupling Nitrogenous Organic Wastewater Treatment and Biorefinery via N‐Cycling Bacterium
The vast reservoir of nitrogenous organic pollutants in industrial wastewaters can serve as untapped carbon‐nitrogen resources. This study employs the newly discovered Paracoccus sp. ZQW‐1 as a versatile chassis to simultaneously achieve N‐methylpyrrolidone (NMP) wastewater depuration and polyhydroxybutyrate (PHB) synthesis.
Ziqian Wang +3 more
wiley +1 more source
Multi-omics reveals the regulatory effects of Chinese herbal medicine substrates on secondary metabolite biosynthesis in <i>Inonotus glomeratus</i>. [PDF]
Peng C +9 more
europepmc +1 more source
ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao +19 more
wiley +1 more source
Chemical clues to infection: A pilot study on the differential secondary metabolite production during the life cycle of selected <i>Cordyceps</i> species. [PDF]
Charria Girón E +8 more
europepmc +1 more source
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen +12 more
wiley +1 more source
Genome Analysis of <i>Alternaria alstroemeriae</i> L6 Associated with Black Spot of Strawberry: Secondary Metabolite Biosynthesis and Virulence. [PDF]
Zhang L +10 more
europepmc +1 more source
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan +16 more
wiley +1 more source
Effects of bioreactor inoculation method on secondary metabolite production and morphological characteristics of Streptomyces rimosus in microparticle-enhanced cultivation (MPEC). [PDF]
Ścigaczewska A, Boruta T, Bizukojć M.
europepmc +1 more source

