Mycotoxins and Other Secondary Metabolites Produced in vitro by Penicillium paneum Frisvad and Penicillium roqueforti Thom Isolated from Baled Grass Silage in Ireland [PDF]
Auerbach H. +45 more
core +2 more sources
Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li +3 more
wiley +1 more source
Secondary Metabolites Predict Diazotrophic Cyanobacteria: A Model-Based Cheminformatic Approach. [PDF]
Young J, Nawaz T, Gu L, Zhou R.
europepmc +1 more source
SECONDARY METABOLITES OF OCIMUM GRATISSIMUM AND THEIR BIOLOGICAL ACTIVITIES
Deeptanjali Sahoo, Ajay Kumar
openalex +1 more source
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong +15 more
wiley +1 more source
Transcriptome and metabolome reveal the accumulation of secondary metabolites in different species of Dioscorea. [PDF]
Li WY +6 more
europepmc +1 more source
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang +11 more
wiley +1 more source
Biological control of fusarium head blight in wheat using secondary metabolites of Bacillus subtilis BS-Z15. [PDF]
Zhao J +8 more
europepmc +1 more source
Enhanced Antioxidant Activity and Secondary Metabolite Production in Tartary Buckwheat under Polyethylene Glycol (PEG)-Induced Drought Stress during Germination [PDF]
Md Shakhawat Hossain +12 more
openalex +1 more source
The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu +16 more
wiley +1 more source

